Can I take Aspirin and Ramapril together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking aspirin and ramipril together can sometimes make the ramipril less effective at lowering your blood pressure. There is also a small risk that the combination could affect how well your kidneys work, especially if you are older, dehydrated, or already have kidney problems.
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Why this happens
Ramipril works by relaxing blood vessels, partly through a substance called prostaglandin. Aspirin (especially at higher doses) blocks the production of this substance, which can stop ramipril from working as well. Both drugs can also reduce blood flow to the kidneys.
What you should do
For most people taking low-dose aspirin (75mg to 150mg) for heart protection, this combination is safe and commonly prescribed. However, you should have your blood pressure and kidney function checked regularly by your doctor. Avoid taking high-dose aspirin (for pain relief) frequently without speaking to your GP. Ensure you stay well-hydrated.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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