Can I take Lactulose and Oxypro together?
Drug interaction guide
Originally published 25 Jan 2026
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
- Langue
- Discussion
Oxypro (oxycodone) is an opioid painkiller that commonly causes constipation as a side effect. Lactulose is a laxative used to treat this constipation. While they are often prescribed together for this reason, the oxycodone is essentially 'fighting' against the laxative, which may make the lactulose less effective than usual.
Dans cet article :
Poursuivre la lecture ci-dessous
Why this happens
Oxypro (oxycodone) slows down the movement of the digestive system (gut motility). Lactulose works by drawing water into the bowel to soften stools and stimulate movement. These two medications have opposing effects on the speed of your digestive tract.
What you should do
It is safe and very common to take these together, but you should monitor your bowel habits. If you remain constipated despite taking lactulose, speak to your doctor or pharmacist, as you may need a different type of laxative (such as a stimulant laxative) to counteract the effects of the Oxypro. Ensure you drink plenty of water.
Poursuivre la lecture ci-dessous
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Traitement et médicaments
Can I take Hydroxycarbamide and Hydroxychloroquine together?
Both hydroxycarbamide and hydroxychloroquine can lower your blood cell counts. Taking them together may increase the risk of developing serious infections, anaemia (low red blood cells), or bruising and bleeding problems. There is also a small risk that both medications could affect your heart rhythm or increase the risk of skin reactions.
Traitement et médicaments
Can I take Esomeprazole and Trazodone together?
Esomeprazole may reduce the amount of trazodone that your body absorbs. This could potentially make trazodone less effective at treating your symptoms (such as depression or sleep issues). Additionally, both medications can rarely affect the electrical activity of your heart, though this risk is generally low.
Poursuivre la lecture ci-dessous
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.
Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne
Inscrivez-vous à la newsletter destinée aux patients
Votre dose hebdomadaire de conseils santé clairs et fiables, rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.