Can I take Lipitor and Zentiva clopidogrel together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking Lipitor (atorvastatin) and clopidogrel together may slightly reduce the effectiveness of clopidogrel in preventing blood clots. However, for most people, the benefits of taking both medicines to prevent heart attacks or strokes far outweigh this small risk.
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Why this happens
Both medicines are processed by the same enzyme in the liver (CYP3A4). Because Lipitor uses this enzyme, it can slow down the process that turns clopidogrel into its active form, potentially making clopidogrel slightly less effective at 'thinning' the blood.
What you should do
You should continue taking both medicines as prescribed by your doctor. Do not stop taking either medication without medical advice, as they are often prescribed together to protect your heart. Your doctor is likely already aware of this interaction and has determined it is safe for you. If you have concerns, or if you notice any new signs of blood clots (such as sudden leg pain or shortness of breath), speak to your GP.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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