Test cutané par piqûre pour allergies
Revu par Dr Caroline Wiggins, MRCGP Dernière mise à jour par Dr Rosalyn Adleman, MRCGPDernière mise à jour 1 juil. 2025
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Dans cette série :AllergiesAnaphylaxieAngio-œdèmeAllergie aux acariens et aux animaux domestiquesAllergie médicamenteuseAntihistaminiques
Le test d'allergie par piqûre cutanée est utilisé pour déterminer la cause de certaines allergies.
En un coup d'œil
A skin prick test checks for allergies to substances like pollen or certain foods.
Your skin is pricked with tiny amounts of suspected allergens.
A positive reaction shows as a red, itchy, raised bump within 20-30 minutes.
The test is generally safe, using only small amounts of allergen.
You should not take antihistamines before the test.
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What is an allergy?
Allergies are the body's response to a substance called an allergen. Allergens themselves may not be harmful. However, in some people, things that are usually harmless can cause a reaction. Examples of allergens are:
Pollens.
Certain foods.
The house dust mite.
Certaines médicaments.
Latex.
The tiny dead skin cells shed by animals (animal dander).
If you are allergic to something, your body's response can vary from very mild (such as a slight itchy rash or runny nose) to a severe life-threatening reaction called anaphylaxie. (See the separate leaflet called Allergies for more details.) Sometimes it is not obvious what it is that you have reacted to, and you will need a test. One type of allergy test is skin prick testing.
How is the skin prick allergy test done?
Retour au sommaireTesting is performed by mixing a small amount of the suspected causes of allergy (such as pollens, dander, foods, etc) with liquid to make a solution. A drop of each solution is then placed on your skin - usually your forearm. Up to 10 or 12 drops of different solutions may be placed on your skin. Your skin is marked to show which liquid has been placed where. Then, the skin beneath each drop is pricked with a very thin needle (lancet). This is usually painless, as just the very surface of the skin is pricked. However, this is enough to let a tiny amount of solution into your skin.
Your skin is then observed for a reaction. If a reaction occurs, it happens within 20-30 minutes.
A reaction is considered to be 'positive' when your skin under a drop of solution becomes red and itchy. Also, a white, raised swelling called a weal (or wheal) surrounds the red central area of any skin reaction. A weal takes about 15-20 minutes to reach a maximum size, and then fades over a few hours.
A reaction is considered to be 'negative' when your skin remains normal. This means that you are not allergic to the substance in the solution.
Remarque: you should not take antihistamines on the day of the test, as they may dampen any allergic response during the test.
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Is skin prick allergy testing safe?
Retour au sommaireSkin prick testing is very safe in most people, and often does not need to be done in hospital clinics. Because such a tiny amount of the allergen is used, the reaction is only very small. For most people the worst that happens is a few itchy bumps for an hour or so. Certain people would not be suitable for skin prick testing. This includes if you have had very severe allergic reactions in the past, or if you have very bad asthme. Skin prick tests are also not usually done if you are pregnant, take certain medications, or have very bad eczéma.
The professionals who do skin prick testing have emergency medicines and equipment standing by for the very rare occasion when someone has a bad reaction. They can reverse the reaction if this happens.
Is skin prick testing the same as patch testing?
Retour au sommaireNo. Patch testing places substances on the surface of the skin. It aims to identify if you have skin allergies. (See the separate leaflet called Patch testing for contact dermatitis.) Skin prick testing checks for allergies that don't necessarily occur on the skin, such as allergies to pollen, foods, etc. It is a way of getting the suspected allergen into the body and in contact with cells of your immune system to see if they react to it.
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Questions fréquemment posées
What is an allergen?
An allergen is a substance that triggers an allergic reaction in some people. While allergens are not inherently harmful, certain individuals' bodies react to them. Common examples include pollens, some foods, house dust mites, specific medicines, latex, and animal dander.
What kind of reactions can I expect from an allergy?
Allergic reactions can vary significantly, ranging from very mild symptoms like a slight itchy rash or a runny nose, to a severe and potentially life-threatening reaction known as anaphylaxis.
How soon will I know the results of a skin prick test?
A reaction, if it occurs, will typically appear within 20-30 minutes after your skin has been pricked with the allergen solution. The maximum size of a positive reaction (a weal) is usually reached within 15-20 minutes, and then it fades over a few hours.
What does a positive result on a skin prick test look like?
If you have a positive reaction, the skin where the drop of solution was applied will become red and itchy. You will also see a white, raised swelling, called a weal (or wheal), surrounding the central red area. This indicates an allergy to that specific substance.
What does a negative result mean in a skin prick test?
A negative reaction means that your skin remains normal where the substance was applied. This indicates that you are not allergic to that particular substance.
Should I avoid any medication before a skin prick test?
Yes, you should not take antihistamines on the day of your skin prick test. Antihistamines can reduce or 'dampen' any allergic response, which could affect the accuracy of the test results.
Who might not be able to undergo skin prick testing?
Skin prick testing is not suitable for everyone. This includes individuals who have a history of very severe allergic reactions, or those with very bad asthma. It's also generally not performed if you are pregnant, taking certain medications, or have very severe eczema.
Lectures complémentaires et références
- Food allergy in children and young people; NICE Clinical Guideline (February 2011, minor update 2018)
- Skin prick testing; DermNet NZ
- Standard operating procedures (SOPs); British Society for Allergy and Clinical Immunology (BSACI). Includes Adult Skin Prick Testing and Paediatric Skin prick testing
- Scala E, Villalta D, Meneguzzi G, et al; Comparison of the performance of Skin Prick and ISAC Tests in the diagnosis of allergy. Eur Ann Allergy Clin Immunol. 2020 Nov;52(6):258-267. doi: 10.23822/EurAnnACI.1764-1489.135. Epub 2020 Nov 3.
- Gupta N, Agarwal P, Sachdev A, et al; Allergy Testing - An Overview. Indian Pediatr. 2019 Nov 15;56(11):951-957.
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À propos de l'auteurVoir la biographie complète

Dr Rosalyn Adleman, MRCGP
MRCGP
Dr Rosalyn Adleman, is an NHS GP working in north London.
À propos du critiqueVoir la biographie complète

Dr Caroline Wiggins, MRCGP
Médecin généraliste, Auteur médical
MBBS Honours (with Distinction), MRCGP (2016), MSc.SEM (with Distinction), BSc (Hons)
Dr Caroline Wiggins is a GP locum currently in the South-West of England.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 30 juin 2028
1 juil. 2025 | Dernière version

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