
Certains aliments peuvent-ils imiter les effets des injections pour perdre du poids ?
Revu par Dr Colin Tidy, MRCGPRédigé par Victoria RawPublié à l'origine 5 May 2026
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Weight loss injections have become a rapidly growing medical option for shedding pounds. To qualify, you must meet specific criteria. If you are eligible, you can pay privately to skip long waitlists. On the NHS, access can take much longer.
If you find yourself stuck in the middle - unable to afford private care but waiting indefinitely for a prescription - there may be another way.
We asked a nutritionist which foods and habits could naturally help curb appetite and support weight loss without medicine.
Foods that help you stay full longer
There are several types of weight loss medicines available, and most work in a similar way. Some prevent your body from absorbing fat, while most modern options focus on curbing hunger. By replicating the ‘fullness hormones’ your body naturally produces, these medicines help you eat less. They also slow down digestion, meaning food stays in your stomach longer and keeps you feeling full well after a meal.
Helena Barham-Coppola, nutritional therapist and founder of Nourish&Be, London, UK, explains that for those seeking foods that act as a ‘speed bump’ for hunger, there are three key nutritional components worth exploring to sustain fullness.
Helena Barham-Coppola

Barham-Coppola identifies these three pillars as:
Fibre - an undigestible carbohydrate that bulks out your poo, supports your gut health, slows gastric emptying, and keeps you fuller for longer than comparable low-fibre meals.
Some dietary fats - such as those found in olive oil, avocado, oily fish, and fermented dairy. Certain fats trigger your natural 'fullness' hormones cholecystokinin (CCK) and peptide-YY (PYY), which signal your brain that you’ve had enough to eat and tell your stomach to slow down its digestion.
Protéines - this is one of the best ways to feel full and keep food in your stomach longer. It works by revving up your natural GLP-1 production - which is the exact same biological pathway that modern weight loss shots are designed to target.
“There is some research suggesting that both protein and calcium together induce enhanced GLP-1 release naturally, as the receptors in your gut respond to calcium and amino acids,” she adds. “Excellent sources of calcium can be found in fermented dairy, tofu, tahini, almonds, and broccoli.”type: embedded-entry-inline id: 3Ockuvt5QSkHRZiUekeS9k
The best order to eat foods for appetite control
To maximise the effects of foods that may naturally mimic weight loss medicine, the order in which you eat them can be surprisingly important.
Barham-Coppola recommends you start your day off with a protein-packed breakfast - for example, boiled eggs, some Greek yoghurt, chicken breast, salmon, or scrambled tofu. Since protein sends a powerful ‘fullness’ signal to your brain that takes roughly 20 minutes to activate, eating it early gives your body a head start on appetite control.
She explains that protein triggers a wave of ‘fullness' hormones that tell your brain to stop eating and your stomach to slow down. By making protein the star of your breakfast, you stabilise your blood sugar for the rest of the morning. It also shuts off ghrelin, the hormone that makes your stomach growl. Because your energy stays steady, you won't face the mid-morning sugar crash that usually leads to reaching for snacks.
“Starting your meal with a few bites of protein can be a great way to use this chemical signal to your advantage in weight loss,” says Barham-Coppola. “All alongside some veggies and complex carbs - depending on the person.”
According to Barham-Coppola, because your body can’t digest fibre, if you eat your vegetables early on in your meal - before or alongside protein - they can act like a protective net that catches sugar and slows its entry into your bloodstream.
“This is the reason why eating an apple can have a minimal blood sugar spike, while eating 2–3 teaspoons of pure sugar - the roughly 10–15 grams of sugar in an apple - can lead to blood sugar spikes and crashes,” she says.
“Fibre also slows gastric emptying and promotes satiety through physical bulk in the stomach. Dietary fibre can also promote the secretion of natural GLP-1.”1
Keep meals interesting to avoid junk food temptation
Trying to stick to an eating plan that prioritises certain foods over others may lead to boredom over the long term if you don't think outside the box in terms of variety.
Barham-Coppola explains that the monotony of a meal, or a series of similar meals, can lead to a decrease in dopamine - your ‘feel-good’ hormone - in response to flavours.
“Ultra-processed food (UPF) such as junk food is often manufactured to be as humanly palatable as possible, with snack culture going wild,” she says. “Perhaps the easiest way to overeat is by eating lots of different UPF snacks - small portions so your brain never gets bored, and all engineered for dopamine reward and low satiety levels thanks to stripped fibre.
“This is also seen with 'the buffet effect' - too many options and a desire to try it all, with each new flavour and texture bringing a potential dopamine hit in the brain.”
Barham-Coppola advises that you don’t deprive yourself of flavour - season your food with herbs and spices and steer clear of UPFs and buffets where possible.
Can everyone biologically manage hunger in this way?
It’s widely accepted that what works for one person may not work for another. Often, it is not a simple case of ‘eat less and eat the right things’. The phrase "just try harder" has haunted many people navigating a weight loss journey - especially those whose genetics are predisposed to make losing weight more difficult than it is for others.
Barham-Coppola addresses this by explaining that some people do have a naturally higher ‘set point’ for weight. This is due, in part, to genetics, but it is also influenced by early-life exposures and the health of their parents prior to conception.
“The body often responds to caloric restriction with stronger hunger signals,” she says. “Another important point to remember is that weight and fat mass can be totally independent of metabolic health. So for someone with a higher set point, that doesn’t mean they should give up.
“Prioritise healthy eating for the wealth of other benefits it provides - including metabolic stability and mental wellbeing. Body shape isn’t everything.”
Barham-Coppola warns that for those living in environments where UPFs are the norm, the struggle to lose weight often becomes a battle against their surroundings. This is where weight loss injections can offer a bridge, but they are most effective when paired with a long-term plan. Without that foundational support, there is a significant chance that weight will return once you stop taking the medicine.
Can we manage hunger this way forever without medicine?
Using these biological ‘hacks’ can take you a long way towards finding a healthy weight, but, as Barham-Coppola describes, it’s rarely as simple as a math’s equation.
She explains that when you cut calories to lose weight, your body eventually senses ‘scarcity’ and triggers a survival mechanism. It begins to lower your metabolism to preserve energy - which is why many people hit a weight loss plateau after a few weeks, even if they haven't changed their routine.
“To overcome this, I often recommend a weekly ‘treat meal’,” she says. “This is really beneficial from a psychological perspective too, as constant restriction can have a negative effect on the mind. It serves to remind your body that it is safe, that it is not living in a famine, and it can continue to lose weight, if that is your goal.”
3 simple steps to test your natural fullness signals today
If you’re curious about testing your own 'natural' fullness signals today without medicine, Barham-Coppola concludes with three tips to help you dial down your food noise.
Practice mindful eating - we often eat while distracted, scrolling through phones or walking down the street, which blocks your brain from registering satiety signals. To fix this, focus solely on your meal. Take a moment to actually look at and connect with your food. Expressing gratitude for the journey that brought the meal to your plate can further strengthen this connection.
Sequence your plate - start with protein and vegetables, leaving complex carbohydrates and fruit for the end of the meal. Above all, avoid UPFs, as they are literally engineered to bypass your natural fullness signals.
Prioritise regular meals - don’t skip meals. Keeping them consistent and centred on protein and fibre helps soothe your nervous system. This is crucial because nothing disrupts blood sugar control and appetite quite like cortisol - your stress hormone.
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Questions fréquemment posées
What are 'fullness hormones' and how do they work?
Fullness hormones are natural signals your body produces that tell your brain you've had enough to eat and signal your stomach to slow down digestion. Weight loss medicines often work by replicating these hormones to help you feel full longer and eat less.
Are there specific dietary fats that help with feeling full?
Yes, certain dietary fats, such as those found in olive oil, avocado, oily fish, and fermented dairy, can trigger your natural fullness hormones cholecystokinin (CCK) and peptide-YY (PYY). These hormones signal to your brain that you've eaten enough and tell your stomach to slow down its digestion.
How does calcium contribute to feeling full?
There is some research suggesting that both protein and calcium together can enhance the natural release of GLP-1, a hormone that promotes fullness. This is because the receptors in your gut respond to both calcium and amino acids. Excellent sources of calcium include fermented dairy, tofu, tahini, almonds, and broccoli.
What is 'the buffet effect' and how does it relate to overeating?
The buffet effect refers to the tendency to overeat when presented with many different food options. Each new flavour and texture can provide a potential dopamine hit in the brain, making it harder to stop eating. This is similar to how ultra-processed foods are engineered to provide constant stimulation and low satiety, encouraging overconsumption.
Why is it important to keep meals interesting?
Keeping meals interesting by varying flavours and textures helps prevent boredom and a decrease in dopamine response to food. Monotony in meals can lead to a desire for more stimulating, often ultra-processed, foods. Using herbs and spices can enhance flavour without resorting to unhealthy options.
À propos de l'auteurVoir la biographie complète

Victoria Raw
Auteur de chroniques
Licence (Hons), Littérature anglaise
Victoria est rédactrice de contenu chez Patient, avec des intérêts particuliers pour le bien-être mental, les tendances sociétales et l'impact de la technologie sur notre santé.
Victoria a collaboré avec diverses associations caritatives tout au long de sa carrière, y compris Ovarian Cancer Action, Scleroderma and Raynaud's UK, St John Ambulance, Andy's Man Club, la RSPCA et Barnardo's. Elle a également travaillé avec de grandes marques de distribution telles que Marks and Spencer, Tesco et Morrisons, ainsi que des géants du divertissement comme Disney et Warner Bros.
À propos du critiqueVoir la biographie complète

Dr Colin Tidy, MRCGP
Médecin généraliste, Auteur médical
MBBS, MRCGP, MRCP (Paediatrics), DCH
Le Dr Colin Tidy est un médecin du NHS, basé dans l'Oxfordshire.
Historique de l'article
Les informations sur cette page sont examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 5 mai 2027
5 May 2026 | Publié à l'origine
Écrit par :
Victoria RawRevu par
Dr Colin Tidy, MRCGP

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