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Can I take 1.5mg and Trulicity together?

Drug interaction guide

Taking Ozempic (semaglutide) and Trulicity (dulaglutide) together can cause your blood sugar levels to drop too low (hypoglycaemia). It also significantly increases the risk of severe side effects like intense nausea, vomiting, and dehydration.

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Why this happens

Both Ozempic and Trulicity belong to the same class of medicine (GLP-1 receptor agonists). They work in the exact same way. Taking both is essentially a double dose, which over-stimulates the pancreas and slows down your digestion too much.

Do not take these two medicines together. They are designed to be used one or the other, never both at the same time. If you have been prescribed both, contact your doctor or pharmacist immediately to clarify your treatment plan. If you feel shaky, sweaty, or confused (signs of low blood sugar), eat something sugary right away.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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