Can I take 1 and Metformin together?
Drug interaction guide
Originally published 14 Mar 2026
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Drinking alcohol while taking metformin can increase the risk of a rare but very serious condition called lactic acidosis. It can also make you more likely to experience low blood sugar (hypoglycaemia).
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Why this happens
Metformin and alcohol both affect how your liver processes glucose (sugar) and lactic acid. Alcohol can prevent the liver from clearing lactic acid from your blood, leading to a dangerous build-up. It also stops the liver from releasing sugar into the blood, which can cause your blood sugar levels to drop too low.
What you should do
Back to contentsIt is best to avoid or strictly limit alcohol while taking metformin. You should never drink alcohol on an empty stomach while on this medication. If you feel very weak, tired, nauseated, or have a fast heartbeat after drinking, seek medical help immediately.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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