Can I take 10 and Mefenamic acid .mg together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking alcohol and mefenamic acid together significantly increases your risk of developing stomach ulcers or bleeding in your digestive tract. It can also increase the strain on your kidneys.
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Why this happens
Mefenamic acid is a Non-Steroidal Anti-Inflammatory Drug (NSAID) that can irritate the lining of the stomach. Alcohol also irritates the stomach lining. When used together, they have an 'additive' effect, making damage much more likely. Both substances also affect how the kidneys filter blood.
What you should do
Back to contentsIt is best to avoid or strictly limit alcohol while taking mefenamic acid. If you experience any sharp stomach pain, black tarry stools, or vomit that looks like coffee grounds, stop taking the medicine and contact a doctor immediately.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
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Taking fluoxetine with Abilify (aripiprazole) can significantly increase the amount of Abilify in your bloodstream. This makes you much more likely to experience side effects such as extreme sleepiness, restlessness (feeling like you cannot sit still), uncontrollable body movements (tremors or twitching), and dizziness. There is also a small but serious risk of a heart rhythm problem called QT prolongation.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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