Can I take 10 and Ramipril together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking ibuprofen (Nurofen) and ramipril together can make your blood pressure medicine less effective. More importantly, it significantly increases the risk of kidney problems and can cause your potassium levels to become dangerously high.
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Why this happens
Ramipril works by relaxing blood vessels, while ibuprofen can cause the body to retain salt and water and constrict blood flow to the kidneys. When used together, they can put a lot of strain on the kidneys and prevent them from filtering waste properly.
What you should do
Back to contentsYou should avoid taking ibuprofen while on ramipril unless your doctor specifically tells you to. If you need pain relief, paracetamol is usually a safer choice. If you have already taken them together and notice you are passing less urine than usual, have swelling in your ankles, or feel unusually tired, contact your GP.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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