Can I take 100 and Osteomol together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking these two medicines together significantly increases your risk of paracetamol overdose and severe liver damage. Both products contain paracetamol as their active ingredient. Taking them at the same time is effectively doubling your dose, which can be fatal.
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Why this happens
Both '100' (likely referring to Paracetamol 100mg or a similar strength) and Osteomol contain paracetamol. Osteomol is a high-strength, sustained-release version of paracetamol (665mg per tablet). When you take both, the total amount of paracetamol in your blood can quickly reach toxic levels that the liver cannot process safely.
What you should do
Back to contentsDo not take these two medicines together. Check the packaging of all your medicines to ensure you are not taking more than one product containing paracetamol. The maximum dose for an adult is 4000mg (4 grams) in any 24-hour period. If you have already taken both, seek medical advice immediately, even if you feel well, as liver damage can take a few days to show symptoms. Additionally, it is best to avoid or strictly limit alcohol when taking paracetamol, as combining them increases the risk of liver damage.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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