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Can I take 2.5 and Vitamin c together?

Drug interaction guide

There is no known interaction between Eliquis (apixaban) and Vitamin C (ascorbic acid). Taking these two together is generally considered safe.

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Why this happens

Vitamin C does not affect the way Eliquis is broken down by the liver, nor does it interfere with the way Eliquis prevents blood clots.

You can take Eliquis and Vitamin C together. However, always stick to the recommended daily dose of Vitamin C, as extremely high doses (well above 2,000mg) can sometimes cause stomach upset or diarrhoea, which might affect how well your body absorbs your medications.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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