Can I take 50 and Naproxen bp together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking these two medicines together significantly increases your risk of developing serious stomach problems, such as stomach ulcers, inflammation of the stomach lining (gastritis), or internal bleeding. It can also put extra strain on your kidneys.
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Why this happens
Both 50 (aspirin) and naproxen belong to the same family of medicines called NSAIDs (non-steroidal anti-inflammatory drugs). They work by blocking the same enzymes in the body. When you take both, you are essentially 'double-dosing' on this effect, which removes the protective lining of the stomach and reduces blood flow to the kidneys. Additionally, naproxen can interfere with aspirin's ability to protect your heart.
What you should do
Back to contentsYou should not take these two medicines together unless specifically instructed to do so by your doctor. If a doctor has prescribed both, they may also prescribe a 'stomach protector' medicine (like omeprazole). If you are taking these for pain, speak to a pharmacist or doctor about safer alternatives, such as paracetamol. Seek medical help immediately if you notice black, tarry stools or vomit that looks like coffee grounds.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Can I take Abilify and Fluoxetine together?
Taking fluoxetine with Abilify (aripiprazole) can significantly increase the amount of Abilify in your bloodstream. This makes you much more likely to experience side effects such as extreme sleepiness, restlessness (feeling like you cannot sit still), uncontrollable body movements (tremors or twitching), and dizziness. There is also a small but serious risk of a heart rhythm problem called QT prolongation.

Treatment and medication
Can I take Amlodipine and Omemprazole together?
There is no significant interaction between amlodipine and omeprazole. It is generally safe to take these two medicines together.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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