Can I take Abilify and Zoloft together?

Why this happens

Zoloft can slow down the way your liver processes Abilify (by blocking an enzyme called CYP2D6). This causes Abilify to build up in your system. Additionally, both drugs affect a brain chemical called serotonin, which can lead to an over-accumulation.

You should use caution when taking these together. Your doctor may need to adjust your dose of Abilify. If you feel unusually sleepy, faint, or notice twitching or uncontrollable movements, contact your doctor. Seek immediate medical help if you experience high fever, sweating, shivering, or a very fast heartbeat.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.