Can I take Acetaminophen and Levocetirizine together?

Why this happens

Paracetamol is a painkiller and fever reducer, while levocetirizine is a non-drowsy antihistamine. They are processed by different pathways in the liver and do not interfere with how the other is absorbed or removed from the body. While levocetirizine is designed to be non-sedating, a small number of people still feel sleepy when taking it; paracetamol can also rarely cause tiredness, leading to a possible mild additive effect on your energy levels.

You can take these two medicines together. It is best to avoid or strictly limit alcohol while taking these medicines, as alcohol can increase the risk of liver damage from paracetamol and increase drowsiness from levocetirizine. If you feel sleepy or dizzy after taking them, do not drive or operate machinery.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.