Can I take Acetaminophen and Losartan together?

Why this happens

Paracetamol can sometimes interfere with certain chemicals in the body called prostaglandins. These chemicals help keep blood vessels open and help the kidneys work properly. Because losartan also works on the blood vessels and kidneys, using both might slightly counteract the blood-pressure-lowering effect of losartan or put a small amount of extra strain on the kidneys.

You can take these medicines together, but it is best to use paracetamol only when needed and at the lowest dose that works for you. If you need to take paracetamol every day for more than a few days, you should have your blood pressure checked by your GP or pharmacist to make sure it is still well-controlled. Always stay well-hydrated. It is best to avoid or strictly limit alcohol when taking paracetamol, as combining them increases the risk of liver damage.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.