Can I take Acetaminophen and Sertraline together?

Why this happens

There are no significant pharmacokinetic interactions (how the body processes the drugs) or pharmacodynamic interactions (how the drugs affect the body) between paracetamol and sertraline. They are broken down by different pathways in the liver.

You can take paracetamol while taking sertraline. Always stick to the recommended dose of paracetamol (usually one or two 500mg tablets up to four times in 24 hours). It is best to avoid or strictly limit alcohol when taking paracetamol, as combining them increases the risk of liver damage. If you find you need to take paracetamol every day for more than a few days, speak to your doctor or pharmacist.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.