Puis-je prendre l'Amlodipine et l'Apixaban ensemble ?

Pourquoi cela se produit

Both drugs are processed by the same enzyme in the liver (CYP3A4) and a transport protein (P-gp). Amlodipine can slightly slow down how quickly the body clears apixaban, leading to a minor increase in the amount of apixaban in your system.

You can usually take these medicines together, but you should be aware of the signs of bleeding. Contact your doctor if you notice unusual bruising, nosebleeds, bleeding gums, or blood in your urine or stools. Do not stop taking either medication without consulting your healthcare provider.

Risque de saignement et chirurgie

You must tell your doctor or dentist you are taking apixaban before any procedure or surgery, as it increases your risk of serious bleeding. Do not stop taking it without medical advice, as this increases your risk of a blood stroke.

Liver problems

If you have liver disease, amlodipine must be used with extreme caution as it is broken down slowly by the liver, which can lead to a dangerous build-up of the medicine in your body.

Jus de pamplemousse

Grapefruit juice can increase the amount of amlodipine in your blood, which may lower your blood pressure too much and increase the risk of side effects like headaches or swollen ankles. It is best to avoid drinking large amounts of grapefruit juice while taking this medicine.

Alcool

While there is no direct interaction, drinking alcohol can lower your blood pressure (adding to the effect of amlodipine) and increase the risk of stomach bleeding (when combined with apixaban). It is best to keep your alcohol intake within the recommended

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Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.