Can I take Amlodopine and Apixaban together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking amlodipine and apixaban together may slightly increase the level of apixaban in your blood. This could potentially increase the risk of bleeding or bruising, although for most people, this effect is very small.
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Why this happens
Both drugs are processed by the same enzyme in the liver (CYP3A4) and a transport protein (P-gp). Amlodipine can slightly slow down how quickly the body clears apixaban, leading to a minor increase in the amount of apixaban in your system.
What you should do
You can usually take these medicines together, but you should be aware of the signs of bleeding. Contact your doctor if you notice unusual bruising, nosebleeds, bleeding gums, or blood in your urine or stools. Do not stop taking either medication without consulting your healthcare provider.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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