Can I take Aspirin and Levothyroxine together?

Why this happens

Levothyroxine travels through your bloodstream mostly attached to proteins. Aspirin can 'bump' the levothyroxine off these proteins, leaving more 'free' or active hormone in your system. This can temporarily change your thyroid hormone levels.

You can usually take these together, but it is best to avoid taking very high doses of aspirin (over 2g per day) regularly. If you are starting a new daily aspirin routine, inform your doctor so they can monitor your thyroid levels if necessary. If you feel symptoms of an overactive thyroid (like palpitations or anxiety), speak to your GP.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.