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Puis-je prendre de l'Aspirine et de la Quétiapine ensemble ?

Guide d'interaction médicamenteuse

Taking aspirin and quetiapine together may increase your risk of bleeding, particularly in the stomach or gut. It can also increase the risk of feeling dizzy or faint when you stand up.

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Pourquoi cela se produit

Aspirin thins the blood and can irritate the stomach lining, while quetiapine can sometimes interfere with how platelets (the cells that help blood clot) work. Additionally, both medications can cause a drop in blood pressure when standing, which may lead to dizziness.

You should use this combination with caution. Watch for signs of unusual bleeding, such as easy bruising, dark or 'tarry' stools, or coughing up blood. To avoid dizziness, try to stand up slowly from a sitting or lying position. If you have a history of stomach ulcers, speak to your doctor before taking aspirin.

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Asthme

Ne prenez pas d'aspirine si vous avez des antécédents d'asthme déclenché par l'aspirine ou d'autres anti-inflammatoires non stéroïdiens (AINS), car cela peut provoquer une crise d'asthme potentiellement mortelle.

Children and teenagers under 16

Never give aspirin to children or teenagers under 16 unless specifically prescribed by a doctor, due to the risk of Reye’s syndrome, a rare but fatal condition affecting the brain and liver.

Suicidal thoughts and self-harm

Quetiapine can increase the risk of suicidal thoughts or self-harm, particularly in young adults (under 25). You must tell someone you trust or seek medical help immediately if your mood changes or you have thoughts of hurting yourself.

Heart disease (specifically heart rhythm disorders)

Quetiapine can affect your heart rhythm (QT prolongation). This risk is higher if you already have heart disease or take other medicines that affect the heart. Seek immediate medical help if you experience palpitations, fainting, or a racing heartbeat.

Drowsiness and impaired coordination

Quetiapine causes significant drowsiness and can affect your balance. Do not drive or operate machinery until you know how it affects you, and be careful to avoid falls, especially when getting up from a sitting or lying position.

Diabetes and blood sugar control

Quetiapine can cause a significant increase in blood sugar levels, even if you are not diabetic. If you have diabetes, you must monitor your blood sugar more closely as your medication dose may need adjusting.

Alcool

Drinking alcohol while taking aspirin increases the risk of developing stomach irritation, ulcers, and bleeding in the digestive tract. It is best to limit or avoid alcohol.

It is best to avoid or strictly limit alcohol while taking quetiapine. Combining alcohol with this medicine can significantly increase drowsiness and dizziness, making you more likely to fall or have an accident. Both substances are processed by the liver, and combining them can put extra strain on your system.

Jus de pamplemousse

You should avoid drinking grapefruit juice or eating grapefruit while taking quetiapine. Grapefruit contains compounds that interfere with how your body breaks down this medicine. This can cause the levels of quetiapine in your blood to rise to potentially dangerous levels, increasing the risk of serious side effects.

Caféine (Café, Thé, Boissons Énergisantes)

Caffeine can interfere with how quetiapine works. It may reduce the effectiveness of the medicine or worsen certain side effects like restlessness. If you consume a lot of caffeine, talk to your doctor before making any sudden changes to your intake, as this can also affect your medicine levels.

Repas riches en graisses

If you are taking the extended-release (XL) version of quetiapine, you should avoid taking it with a very heavy or high-fat meal. This can cause the medicine to be absorbed into your system too quickly (known as 'dose dumping'), which increases the risk of side effects. It is usually best to take it without food or with a light snack.

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Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 janv. 2026 | Originally published
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