Puis-je prendre de l'Atorvastatine et de l'extrait de chardon-Marie ensemble ?

Caution is advised when taking atorvastati and milk thistle together. Combining them may increase the amount of atorvastatin in your system, increasing the risk of atorvastatin side effects.

Pourquoi cela se produit

Milk thistle contains a compound called silymarin. Silymarin can interfere with certain proteins (transporters) and enzymes in the liver that are responsible for breaking down and removing atorvastatin from your body.

If the liver cannot process the statin as quickly as usual, the drug levels can rise.

• Use caution if combining these two medicines.

• If you decide to take milk thistle, monitor yourself closely for any new or unusual muscle pain, tenderness, or weakness, as well as any yellowing of the skin or eyes (jaundice).

• It is best to inform your doctor or pharmacist before starting milk thistle so they can ensure your statin dose remains appropriate for you.

Grossesse

Vous ne devez pas prendre de l'atorvastatine si vous êtes enceinte ou prévoyez de le devenir, car cela peut causer des dommages graves à un bébé à naître. Utilisez une contraception efficace pendant que vous prenez ce médicament.

Muscle disorders - atorvastatin

You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, as this can rarely lead to serious kidney damage.

Hormone-sensitive conditions

Avoid milk thistle if you have a history of hormone-sensitive cancers or conditions (such as breast cancer or endometriosis), as it may have oestrogen-like effects that could worsen these conditions.

Jus de pamplemousse

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This can increase your risk of side effects, such as muscle pain or liver problems.

You should avoid drinking large quantities (more than 1.2 litres daily), but it is safest to avoid it altogether while taking this medicine.

Alcool

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver damage and may raise triglyceride levels, which can counteract the benefits of the medicine.

It is advised to keep alcohol intake within recommended limits.

Taking multiple medicines? Our Vérificateur d'Interactions Médicamenteuses helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Avertissement

Ces informations sont fournies à des fins éducatives générales uniquement et ne doivent pas être considérées comme un substitut aux conseils médicaux professionnels. Consultez toujours votre médecin généraliste, votre pharmacien ou un autre professionnel de santé qualifié avant de prendre des décisions concernant vos médicaments. Les circonstances individuelles peuvent varier, et seul un professionnel de santé connaissant votre historique médical peut fournir des conseils personnalisés.