Can I take Atorvastatin and Sertraline together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking atorvastatin and sertraline together may slightly increase the levels of atorvastatin in your blood. This can increase the risk of side effects, particularly muscle pain or weakness.
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Why this happens
Both medications are processed by the same enzymes in the liver (specifically CYP3A4). Because they are 'competing' for the same processing pathway, the body may break down atorvastatin more slowly than usual.
What you should do
You can usually take these together, but you should be vigilant. Tell your doctor if you experience any unexplained muscle pain, tenderness, or weakness, especially if you also feel generally unwell or have a fever. Your doctor may monitor your liver function or muscle enzymes (CK levels) via blood tests.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
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