Can I take Duloxetine and Lamotrigine together?

Why this happens

Both medications affect chemicals in the brain. While they work in different ways, their effects on the central nervous system can add together (an additive effect), making side effects like dizziness or sleepiness more likely. There is also a theoretical, though low, risk regarding how these drugs affect serotonin levels.

This combination is generally considered safe to take together, but you should be aware of how you feel. If you experience significant dizziness, confusion, or unusual changes in your mood or coordination, contact your doctor. Do not stop taking either medication without consulting your healthcare provider first, as stopping suddenly can cause withdrawal symptoms or a return of your original symptoms.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.