Can I take Metformin and Quetiamine together?
Drug interaction guide
Originally published 12 May 2026
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Taking quetiapine may make your metformin less effective at controlling your blood sugar levels. This can lead to higher blood sugar (hyperglycaemia).
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Why this happens
Quetiapine is an antipsychotic medication that can interfere with how your body handles insulin and sugar. It can cause the body to become less sensitive to insulin or reduce the amount of insulin produced, which directly opposes the blood-sugar-lowering effects of metformin.
What you should do
Back to contentsYou should monitor your blood sugar levels more frequently when starting, stopping, or changing the dose of quetiapine. If you notice your blood sugar readings are consistently high, or if you experience increased thirst or frequent urination, contact your doctor. They may need to adjust your metformin dose.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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