Can I take Nefopam and Propranolol together?

Why this happens

Nefopam has 'sympathomimetic' properties, meaning it can increase heart rate and blood pressure. Propranolol is a beta-blocker used to slow the heart rate and lower blood pressure. These two drugs have opposing effects on the cardiovascular system, which can lead to unpredictable changes in heart rhythm. Additionally, both drugs can contribute to a dry mouth and other similar side effects.

You should use this combination with caution. If your doctor has prescribed both, monitor your heart rate and blood pressure regularly. Seek medical advice if you feel your heart is racing, if you feel dizzy, or if you experience significant blurred vision or trouble urinating.

Asthma or COPD

You must not take this medicine if you have asthma or a history of wheezing. It can cause a severe, life-threatening narrowing of your airways.

Epilepsy or history of seizures

This medicine should be avoided if you have epilepsy or are prone to fits, as it can trigger or worsen seizures.

Urinary retention (e.g. enlarged prostate)

Nefopam can make it very difficult to pass urine. You should not take it if you already have problems emptying your bladder, such as from an enlarged prostate.

Alcohol

Drinking alcohol while taking these medicines can increase drowsiness and dizziness. It may also increase the risk of side effects like blurred vision or feeling faint. It is best to avoid or strictly limit alcohol intake.

Caffeine (Coffee, tea, energy drinks)

Propranolol is often used to treat physical symptoms of anxiety or heart palpitations. Caffeine is a stimulant that can increase your heart rate and blood pressure, which may counteract the effects of propranolol. It is advisable to limit your caffeine intake.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.