Can I take Pregabalin and Venlafaxine together?
Drug interaction guide
Originally published 25 Jan 2026
Répond aux besoins du patient lignes directrices éditoriales
- TéléchargerTélécharger
- Partager
- Langue
- Discussion
Taking pregabalin and venlafaxine together can increase the risk of side effects that affect your central nervous system. You may feel more drowsy, dizzy, or sleepy than usual. It can also lead to difficulty concentrating, confusion, and a higher risk of falls, especially in older adults. In rare cases, it may cause breathing difficulties.
Dans cet article :
Poursuivre la lecture ci-dessous
Why this happens
Both medications have 'depressant' effects on the central nervous system. While they work in different ways, their sedative effects add together (an additive effect), making the overall impact on your alertness and coordination much stronger than if you took either medicine alone.
What you should do
You should use caution when taking these two medicines together. Avoid driving or operating heavy machinery until you know how this combination affects you. It is best to avoid alcohol, as it will make the drowsiness much worse. If you experience extreme sleepiness, confusion, or shallow breathing, contact your doctor immediately.
Poursuivre la lecture ci-dessous
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Clause de non-responsabilité
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Traitement et médicaments
Can I take Esomeprazole and Vitamin c together?
Esomeprazole may slightly reduce how much Vitamin C your body absorbs, but this is generally not a cause for concern for most people.
Traitement et médicaments
Can I take Hydroxycarbamide and Hydroxychloroquine together?
Both hydroxycarbamide and hydroxychloroquine can lower your blood cell counts. Taking them together may increase the risk of developing serious infections, anaemia (low red blood cells), or bruising and bleeding problems. There is also a small risk that both medications could affect your heart rhythm or increase the risk of skin reactions.
Poursuivre la lecture ci-dessous
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
25 janvier 2026 | Publié à l'origine
Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets liés à la santé.
Vous ne vous sentez pas bien ?
Évaluez gratuitement vos symptômes en ligne
Inscrivez-vous à la newsletter destinée aux patients
Votre dose hebdomadaire de conseils santé clairs et fiables, rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
En vous abonnant, vous acceptez notre politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.