Can I take Rosuvastatin and Trazadone together?

Why this happens

Rosuvastatin and trazodone are processed by different pathways in the liver. Rosuvastatin is primarily handled by the CYP2C9 enzyme, while trazodone is mainly processed by the CYP3A4 enzyme. Because they do not compete for the same 'processing machinery', they do not interfere with each other's levels in the blood.

You can continue taking both medicines as prescribed by your doctor. As with any statin (like rosuvastatin), you should always report any unexplained muscle pain, tenderness, or weakness to your doctor, but taking trazodone does not increase the risk of this happening.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.