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Adefovir pour l'hépatite B

Hepsera

Adefovir is an antiviral medicine. You have been prescribed it for chronic hepatitis B infection.

The usual dose is one 10 mg tablet daily. You can take your doses either with or without food.

It is important to take adefovir regularly every day, preferably at the same time each day.

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About adefovir

Type de médicament

Un médicament antiviral

Utilisé pour

Chronic hepatitis B infection in adults

Également appelé

Adefovir dipivoxil; Hepsera®

Disponible en

Tablettes

Hepatitis means inflammation of the liver. Some viruses can cause hepatitis. Hepatitis B is a virus which is carried in your bloodstream to your liver, where it can affect and damage your liver. Following infection with hepatitis B, a few people develop a persistent infection called chronic hepatitis B.

People with chronic hepatitis B usually need treatment to stop or to reduce the activity of the virus. This limits damage to the liver, which is a complication of the infection. One of the types of treatment currently given is an antiviral medicine. Antiviral medicines like adefovir work by stopping the hepatitis B virus from multiplying (replicating); this reduces the amount of the virus in your body.

A doctor who is a liver specialist will usually start the treatment for you. Treatment for chronic hepatitis B usually continues for several years, but can be lifelong. It can include more than one antiviral medicine.

Before taking adefovir

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking adefovir it is important that your doctor knows:

  • Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.

  • Si vous avez un problème de fonctionnement des reins.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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How to take adefovir

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about adefovir, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take adefovir exactly as your doctor tells you to. The usual dose is one 10 mg tablet daily. You can take the tablet either with or without food.

  • Try to take your doses at the same time of day each day, as this will help you to remember to take adefovir regularly.

  • If you are ever sick within one hour of taking a tablet, you should take a second tablet. This is because your body will not have absorbed a sufficient amount of the medicine. If, however, you are sick and it is more than one hour after taking a tablet, you do not need to take a second dose, as your body will have already absorbed the full dose.

  • If you forget to take a dose at your usual time, take it as soon as you remember. However, if you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Tirer le meilleur parti de votre traitement

  • Keep your regular appointments with your doctor. This is so that your progress can be monitored. You will need to have some blood tests from time to time.

  • It is important that you continue to take adefovir regularly. Treatment for hepatitis B can be long-term. Continue to take the tablets, even if you feel well. This is to keep your liver healthy.

  • Treatment with adefovir does not stop you from passing the infection on to others through sexual contact, sharing needles to inject drugs, or from mother to baby. A vaccine is available which protects against hepatitis B and can be offered to your sexual and household contacts who are at risk of being infected. Do not have sex with anyone (especially any sex without using a condom) until they have been fully immunised and have had their blood checked to see that the immunisation has worked.

  • Most people with chronic hepatitis B will be advised to eat a normal healthy balanced diet. However, it is likely you will be advised not to drink alcohol. Alcohol will increase the risk and speed of you developing liver damage.

  • Medicines similar to adefovir have been associated with a serious side-effect in a few people. This is known as lactic acidosis. It is a problem where there is too much lactic acid in the blood. The symptoms associated with it are listed in the next section 'Can adefovir cause problems?'. Although this has occurred in only a very few people, you must let your doctor know straightaway if you develop the symptoms listed below.

  • You must avoid getting pregnant while you are taking adefovir. Make sure you have discussed with your doctor which types of contraception are suitable for you.

  • If you buy any medicines, supplements or herbal remedies 'over the counter', check with a pharmacist that they are suitable to take with adefovir and your other medicines.

  • Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.

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Can adefovir cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with adefovir. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common adefovir side-effects (these affect more than 1 in 10 people)


Que puis-je faire si je suis confronté à cette situation ?

Feeling tired or weak

Ne conduisez pas et n'utilisez pas d'outils ou de machines lorsque vous êtes affecté. Si le problème persiste, consultez votre médecin

Modifications de certains tests sanguins

Votre médecin vérifiera les éléments suivants

Common adefovir side-effects

(ces maladies touchent moins d'une personne sur dix)

Que puis-je faire si je suis confronté à cette situation ?

Feeling sick (nausea) or being sick (vomiting), indigestion, wind, tummy (abdominal) pain

Tenez-vous en à des repas simples - évitez les aliments gras ou épicés. Si le problème persiste, consultez votre médecin

Diarrhée

Boire beaucoup d'eau pour remplacer les liquides perdus

Maux de tête

Buvez beaucoup d'eau et demandez à un pharmacien de vous recommander un analgésique adapté. Si les maux de tête persistent, prévenez votre médecin

Éruption cutanée avec démangeaisons

En cas de troubles, parlez-en à votre médecin

Your doctor will discuss with you the possibility of this medicine causing a problem called lactic acidosis. Let your doctor know straightaway if you develop the following symptoms:

  • Se sentir malade (nausées) ou être malade (vomissements), douleurs abdominales, perte d'appétit, perte de poids, sensation de faiblesse ou d'étourdissement, respiration rapide ou haletante.

Si vous ressentez d'autres symptômes qui pourraient être dus aux comprimés, demandez conseil à votre médecin ou à votre pharmacien.

How to store adefovir

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Prochaine révision prévue : 26 Oct 2025
  • 27 Oct 2022 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
  • 29 mai 2013 | Publié à l'origine

    Auteur: :

    Helen Allen, MPharm
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