Comprimés et médicament liquide d'Amiloride
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 16 déc. 2024
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Amiloride is a 'water' tablet (diuretic).
Ça vous fera aller aux toilettes plus souvent pour uriner.
Les effets secondaires sont généralement légers.
Clinical author's note: Michael Stewart 15/11/2018:Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other blood pressure medicines such as amiloride. It may be available on its own in other countries. For more information see 'Getting the most from your treatment' below or view the Alerte MHRA.
At a glance
Amiloride is a 'water tablet' (diuretic) used to treat water retention and high blood pressure.
It increases urine production but does not cause the body to lose potassium.
Take amiloride as directed by your doctor, usually in the morning.
Avoid 'salt substitutes' as they can increase potassium levels in your body.
Contact your doctor if you become very thirsty or have dry skin, as your dose may need adjusting.
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About amiloride
Type de médicament | Un diurétique épargneur de potassium |
Utilisé pour | Water retention (oedema); high blood pressure |
Aussi appelé | Combination tablets: Co-amilozide (amiloride with hydrochlorothiazide), co-amilofruse (amiloride with furosémide), amiloride with bumetanide; |
Disponible sous forme de | Comprimés et médicaments liquides oraux |
Amiloride belongs to the group of medicines known as potassium-sparing diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water' tablets. Amiloride is called a potassium-sparing diuretic because, unlike some other diuretics, it does not cause your body to lose potassium. It is used to treat hypertension artérielle (hypertension) and also la rétention d'eau (œdème).
Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless and your legs feel puffy. It is commonly caused by heart failure or liver disease. Amiloride prevents the build-up of this fluid by increasing the amount of urine your kidneys produce.
Amiloride can be prescribed as a treatment on its own, or alongside other diuretics. When it is used with other diuretics, it can be prescribed as a combination tablet to help cut down on the number of tablets you need to take each day. Combination tablets include co-amilozide (amiloride with hydrochlorothiazide) and co-amilofruse (amiloride with furosemide).
Before taking amiloride
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking amiloride it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
If you have any problems with the way your kidneys work, or if you have any difficulties passing urine.
Si vous avez le diabète.
Si un médecin vous a informé que vous avez des niveaux élevés de potassium dans votre sang.
If you have a problem with your adrenal glands, called Maladie d'Addison.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take amiloride
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about amiloride and will also provide you with a full list of side-effects which you could experience from taking it.
Take amiloride exactly as your doctor tells you to. Your doctor will ask you to take one dose, or possibly two doses, a day. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.
Amiloride is best taken in the morning. This is because you will find you may need to go to the toilet a couple of times after taking it and this will disturb your sleep if you take it too late in the day. If you have been prescribed more than one dose a day, make sure you take your last dose no later than 6 pm.
You can take amiloride either before or after meals.
If you forget to take a dose of amiloride, take it when you remember unless it is late in the day. If it is after 6 pm in the evening, leave out the missed dose completely and take your next dose when it is due on the following day. Do not take two doses at the same time to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The balance of salts in your blood may be upset by amiloride so your doctor may want you to have a blood test from time to time to check for this.
Les diurétiques vous aident à perdre de l'eau, ce qui vous permet de respirer et de bouger plus facilement. Cependant, si vous perdez trop de liquide, vous pouvez souffrir d'un manque de liquide dans le corps (déshydratation). Cela vous donnera soif et rendra votre peau sèche au toucher et à l'apparence. Informez votre médecin si cela se produit, car votre dose pourrait devoir être ajustée.
Because amiloride is a potassium-conserving diuretic, you should try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.
Treatment with diuretics is usually long-term, so continue to take amiloride unless your doctor advises you otherwise.
Si vous achetez des médicaments 'en vente libre', veuillez vérifier avec un pharmacien qu'ils sont adaptés à votre prise en parallèle de vos médicaments prescrits.
Si vous prenez également de l'hydrochlorothiazide en combinaison avec ce médicament
Des études ont suggéré que prendre des doses plus élevées d'hydrochlorothiazide pendant de longues périodes pourrait augmenter le risque de certains cancers de la peau.
Dites à votre médecin si vous avez déjà été traité pour un cancer de la peau auparavant.
Informez votre médecin de tout grain de beauté nouveau ou modifié, ou de toute marque inquiétante sur votre peau.
Utilisez un écran solaire en cas de fort ensoleillement. N'utilisez pas de lits de bronzage.
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Can amiloride cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with amiloride. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Amiloride side-effects | Que puis-je faire si je ressens cela ? |
Stomach upset, stomach ache | Optez pour des repas simples - évitez les aliments riches ou épicés |
Bouche sèche | Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre |
Feeling dizzy or faint especially when getting up | Se lever plus lentement devrait aider. Si vous commencez à vous sentir étourdi, allongez-vous pour ne pas vous évanouir, puis asseyez-vous quelques minutes avant de vous lever |
Muscle cramps, aches or pains, eyesight problems, a ringing in your ears (tinnitus), headache, skin rash, and feeling tired | Si l'un de ces symptômes devient gênant, informez votre médecin |
Modifications des résultats de certains tests sanguins | Votre médecin peut vérifier cela de temps en temps |
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store amiloride
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous devez subir une opération ou un traitement dentaire, veuillez informer la personne effectuant le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is the main difference between amiloride and other diuretics?
Amiloride is known as a potassium-sparing diuretic. This means that, unlike some other diuretics often called 'water' tablets, amiloride helps your body get rid of excess fluid without causing you to lose potassium. This is important because maintaining the right potassium levels in your body is crucial for your health.
Why would my doctor want me to have blood tests while taking amiloride?
Your doctor may ask you to have blood tests periodically because amiloride can affect the balance of salts in your blood. These tests help ensure that your body's salt levels, particularly potassium, remain within a healthy range, as both too little and too much potassium can be problematic.
I feel very thirsty and my skin is dry. Is this normal when taking amiloride?
Amiloride works by helping your body lose water. If you lose too much fluid, you might become dehydrated, which can make you feel thirsty and cause your skin to look and feel dry. If you experience these symptoms, you should let your doctor know, as your dose of amiloride might need to be adjusted.
Are there any specific foods or products I should avoid while on amiloride?
Yes, because amiloride is a potassium-sparing diuretic, you should try to avoid products with a high potassium content, such as 'salt substitutes'. This precaution helps prevent the level of potassium in your body from becoming too high, which can be harmful.
What should I do if I forget to take a dose of amiloride?
If you forget a dose, take it as soon as you remember, unless it's already late in the day. If it's after 6 pm, you should skip the missed dose completely and take your next dose at its usual time the following day. Never take a double dose to make up for one you missed.
Can I take amiloride at any time of day?
Amiloride is best taken in the morning. This is because it increases the amount of urine you produce, and taking it earlier in the day helps prevent your sleep from being disturbed by needing to go to the toilet frequently. If you take more than one dose daily, ensure your last dose is no later than 6 pm.
What should I do if I'm taking amiloride and start feeling dizzy or faint?
If you start to feel dizzy or faint, getting up slowly can often help. If you feel dizzy, it's best to lie down to prevent fainting, and then sit for a few minutes before standing up again. If these symptoms continue or become troublesome, you should tell your doctor or pharmacist.
Lectures complémentaires et références
- Manufacturer's PIL, Amiloride 5 mg Tablets; Wockhardt UK Ltd, The electronic Medicines Compendium. Dated January 2023.
- Manufacturer's PIL, Amiloride 5 mg/5 ml Oral Solution; Essential Pharma Ltd. The electronic Medicines Compendium. Dated June 2024.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 16 déc. 2027
16 déc. 2024 | Dernière version

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