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Amiloride en comprimés et en liquide

Amiloride is a 'water' tablet (diuretic).

Il vous obligera à aller plus souvent aux toilettes pour uriner.

Les effets secondaires éventuels sont généralement légers.

Clinical author's note: Michael Stewart 15/11/2018:Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other blood pressure medicines such as amiloride. It may be available on its own in other countries. For more information see 'Getting the most from your treatment' below or view the MHRA Alert.

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About amiloride

Type de médicament

A potassium-sparing diuretic

Utilisé pour

Water retention (oedema); high blood pressure

Également appelé

Combination tablets: Co-amilozide (amiloride with hydrochlorothiazide), co-amilofruse (amiloride with furosemide), amiloride with bumetanide;

Disponible en

Comprimés et médicaments liquides oraux

Amiloride belongs to the group of medicines known as potassium-sparing diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water' tablets. Amiloride is called a potassium-sparing diuretic because, unlike some other diuretics, it does not cause your body to lose potassium. It is used to treat high blood pressure (hypertension) and also water retention (oedema).

Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless and your legs feel puffy. It is commonly caused by heart failure or liver disease. Amiloride prevents the build-up of this fluid by increasing the amount of urine your kidneys produce.

Amiloride can be prescribed as a treatment on its own, or alongside other diuretics. When it is used with other diuretics, it can be prescribed as a combination tablet to help cut down on the number of tablets you need to take each day. Combination tablets include co-amilozide (amiloride with hydrochlorothiazide) and co-amilofruse (amiloride with furosemide).

Before taking amiloride

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking amiloride it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • If you have any problems with the way your kidneys work, or if you have any difficulties passing urine.

  • Si vous êtes diabétique.

  • If you have been told by a doctor that you have high levels of potassium in your blood.

  • Si vous avez un problème avec vos glandes surrénales, appelé maladie d'Addison.

  • Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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How to take amiloride

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about amiloride and will also provide you with a full list of side-effects which you could experience from taking it.

  • Take amiloride exactly as your doctor tells you to. Your doctor will ask you to take one dose, or possibly two doses, a day. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.

  • Amiloride is best taken in the morning. This is because you will find you may need to go to the toilet a couple of times after taking it and this will disturb your sleep if you take it too late in the day. If you have been prescribed more than one dose a day, make sure you take your last dose no later than 6 pm.

  • You can take amiloride either before or after meals.

  • If you forget to take a dose of amiloride, take it when you remember unless it is late in the day. If it is after 6 pm in the evening, leave out the missed dose completely and take your next dose when it is due on the following day. Do not take two doses at the same time to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The balance of salts in your blood may be upset by amiloride so your doctor may want you to have a blood test from time to time to check for this.

  • Diuretics help you to lose water, so you can breathe and move more easily. If, however, you lose too much fluid, you may become lacking in fluid in the body (dehydrated). This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted.

  • Because amiloride is a potassium-conserving diuretic, you should try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.

  • Treatment with diuretics is usually long-term, so continue to take amiloride unless your doctor advises you otherwise.

  • If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take alongside your prescribed medicines.

Si vous prenez également de l'hydrochlorothiazide en association avec ce médicament

  • Des études ont suggéré que la prise de doses élevées d'hydrochlorothiazide pendant de longues périodes peut augmenter le risque de certains cancers de la peau.

  • Informez votre médecin si vous avez déjà été traité pour un cancer de la peau.

  • Informez votre médecin de tout grain de beauté nouveau ou modifié ou de toute marque inquiétante sur votre peau.

  • Utilisez un écran solaire en cas de forte exposition au soleil. Ne pas utiliser de banc solaire.

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Can amiloride cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with amiloride. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Amiloride side-effects

Que puis-je faire si je suis confronté à cette situation ?

Stomach upset, stomach ache

S'en tenir à des repas simples - éviter les aliments riches ou épicés

Bouche sèche

Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre.

Feeling dizzy or faint especially when getting up

Getting up more slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few minutes before you stand

Muscle cramps, aches or pains, eyesight problems, a ringing in your ears (tinnitus), headache, skin rash, and feeling tired

If any of these become troublesome, tell your doctor

Modification des résultats de certains tests sanguins

Your doctor may check for these from time to time

Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store amiloride

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Date de la prochaine révision : 16 décembre 2027
  • 16 Dec 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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