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Amiodarone pour les battements de cœur irréguliers

Cordarone X

Amiodarone is used to treat irregular heartbeats. Treatment with it will be started by a heart specialist.

It is very important that you take amiodarone exactly as your doctor tells you to. You will be started on a high dose, for one week only. Your dose will then be reduced over the following two weeks to a maintenance dose.

Amiodarone is likely to cause your skin to become more sensitive to sunlight than normal. Use a sunscreen on the areas of your skin exposed to sunlight.

At a glance

  • Amiodarone is a medicine used to treat irregular heartbeats, also called arrhythmias.

  • It corrects your heart rhythm and can slow a very fast heart rate.

  • Take amiodarone exactly as prescribed by your heart specialist.

  • Regularly see your doctor for check-ups and blood tests to monitor your liver and thyroid.

  • Protect your skin from the sun as amiodarone can increase sun sensitivity.

  • Do not drink grapefruit juice while taking amiodarone.

  • Contact your doctor straight away if you notice yellowing skin, tiredness, a persistent cough, or breathlessness.

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About amiodarone

Type de médicament

An anti-arrhythmic medicine

Utilisé pour

Irregular heartbeats

Aussi appelé

Cordarone X®

Disponible sous forme de

Tablets and injection

Amiodarone is used to treat heart arrhythmias. An arrhythmia is an irregularity in your heartbeat which causes your heart to miss a beat, beat irregularly or beat at the wrong speed. Amiodarone is particularly helpful when other medicines used for the treatment of arrhythmias are unsuitable for some reason.

Amiodarone works by correcting the rhythm of your heart and by slowing your heart if it is beating too fast. It will be prescribed for you by a heart specialist doctor.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking amiodarone it is important that your doctor knows:

  • If you have any heart problems other than your abnormal heart rhythm. In particular, you should let your doctor know if you have been diagnosed with heart failure.

  • If you have problems with your thyroid gland.

  • If you know you have low amounts of potassium in your blood.

  • Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you know you are allergic to iodine.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about amiodarone and will provide you with a full list of the side-effects which you may experience from taking it.

  • Your doctor will tell you what the right dose of amiodarone is for you, and this dose will be printed on the label of the pack of tablets to remind you about what the doctor said to you. It is usual to take 200 mg three times a day for the first week, then 200 mg twice a day for the second week. Your dose may then be reduced to 200 mg each day from the third week. It is very important that you take amiodarone exactly as your doctor tells you to. If you are not sure what dose to take, ask your doctor or pharmacist for advice.

  • Try to take your doses of amiodarone at the same times each day, as this will help you to remember to take them regularly. You can take amiodarone either before or after meals.

  • Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez (sauf s'il est presque l'heure de votre prochaine dose, auquel cas laissez de côté la dose oubliée). Ne prenez pas deux doses ensemble pour compenser une dose oubliée.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check your heart rhythm and monitor your progress. Your doctor will also want to do some blood tests while you are on amiodarone to check your liver and thyroid function.

  • Your doctor is likely to recommend that you have an eyesight test each year. This is because you may develop deposits in your eyes. This is not likely to affect your vision, but if you are a driver you may find that you are dazzled by headlights if you drive at night.

  • Taking amiodarone is likely to cause your skin to become more sensitive to sunlight than normal. Whenever you go outside on bright days (even if it is cloudy, or if it is only for a relatively short period of time), use a sunscreen that has a high sun protection factor and also protects your skin against UVA light. Do not use sunbeds.

  • Do not drink grapefruit juice while you are on amiodarone. This is because a chemical in grapefruit juice can increase the amount of amiodarone in your bloodstream. This makes side-effects more likely.

  • Treatment with amiodarone is usually long-term unless you experience an adverse effect. You should continue to take it unless you are advised otherwise by your doctor.

  • If you are having an operation or any medical/dental treatment, remember to tell the person carrying out the treatment that you are taking amiodarone. It can interfere with some anaesthetics and increase the risk of side-effects.

  • If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable for you to take alongside your other medicines. Many medicines can interfere with the way amiodarone works.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with amiodarone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common amiodarone side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Being dazzled by bright lights, blurred vision

Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines

Se sentir malade (nausée) ou être malade (vomissements)

Eat simple meals - avoid rich or spicy food. Taking your doses after you have eaten some food may help

Common amiodarone side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Changes in the way things taste, shakiness, nightmares, difficulties sleeping, decreased libido, blue/grey marks on areas of your skin exposed to the sun

Si l'un de ces éléments devient problématique, parlez-en à votre médecin

ECG changes, changes to thyroid or liver function tests

Your doctor will monitor for these

Important: there have been some reports of amiodarone causing damage to the liver (hepatotoxicity) and damage to the lungs (pneumonitis). The symptoms of liver damage are yellowing of the skin or the whites of the eyes, and feeling very tired or sick (nausea). The symptoms of lung damage are a persistent cough and breathlessness. If you experience any of these symptoms, you should contact your doctor for advice straightaway.

If you experience any other symptoms which you think may be due to amiodarone, speak with your doctor or pharmacist for further advice.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Questions fréquemment posées

Why is amiodarone prescribed by a heart specialist doctor?

Amiodarone is a powerful medicine specifically used to correct irregular heartbeats and slow a rapid heartbeat. Because it is used to treat complex heart conditions, it requires specialist knowledge and oversight, which is why a heart specialist doctor will prescribe it.

Can I take amiodarone if I have other health issues?

If you have other health issues, it's important to discuss them with your doctor before starting amiodarone. Your doctor needs to know if you have any heart problems other than your abnormal rhythm (especially heart failure), issues with your thyroid gland, low potassium levels in your blood, or a rare blood disorder called porphyria. Being allergic to iodine is also particularly important to mention.

What should I do if I forget to take my amiodarone dose?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, you should skip the missed dose entirely. Never take two doses at once to compensate for a forgotten one.

What kind of regular check-ups will I need while on amiodarone?

While taking amiodarone, you will need regular appointments with your doctor to monitor your heart rhythm and progress. Your doctor will also arrange blood tests to check the function of your liver and thyroid. Additionally, an annual eyesight test is recommended due to possible eye deposits, especially if you drive at night.

Could amiodarone affect my vision, especially when driving?

Amiodarone can cause deposits in your eyes, which, while not likely to affect your overall vision, might make you feel dazzled by headlights when driving at night. If this happens, it's advised not to drive or operate machinery.

Why is it important to tell medical staff I'm taking amiodarone before an operation or dental treatment?

It's crucial to inform anyone performing an operation or medical/dental treatment that you are on amiodarone. This is because amiodarone can interact with some anaesthetics and potentially increase the risk of side-effects.

Are there any drinks or 'over the counter' medicines I should avoid while taking amiodarone?

Yes, you should not drink grapefruit juice as it can increase the amount of amiodarone in your bloodstream, making side-effects more likely. Also, if you buy any medicines without a prescription, always check with a pharmacist to ensure they are safe to take with amiodarone, as many medicines can interfere with how it works.

What are the signs of liver or lung damage I should look out for with amiodarone?

You should contact your doctor straight away if you experience symptoms indicating liver damage, such as yellowing of your skin or eyes, or feeling very tired or sick. For lung damage, look out for a persistent cough and breathlessness.

Lectures complémentaires et références

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 17 mai 2027
  • 2 juin 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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