Aspirine et métoclopramide pour la migraine
MigraMax
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 23 oct. 2023
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MigraMax® helps to ease headache and sickness (nausea and vomiting) during a migraine or during treatment with chemotherapy or radiotherapy.
Take a dose as soon as you feel the start of a migraine attack. Dissolve the contents of one sachet into a small glass of water. You can take a second dose after two hours if needed.
Do not take any other medicines containing aspirin while you are taking this medicine.
En un coup d'œil
MigraMax is a combination medicine containing aspirin and metoclopramide.
It treats headache and sickness during occasional migraine attacks.
Stir one sachet into water and drink it at the start of a migraine.
Do not take more than three sachets in 24 hours.
It should not be taken by anyone under 18 years old.
Talk to your doctor if you experience muscle or movement disorders or allergic reactions.
About aspirin and metoclopramide
Type de médicament | A painkiller with an anti-emetic |
Utilisé pour | The treatment of migraine symptoms; prevention of nausea and vomiting caused by chemotherapy or radiotherapy |
Aussi appelé | MigraMax® |
Disponible sous forme de | Sachets containing powder |
MigraMax® is a combination medicine containing a type of aspirin, called lysine acetylsalicylate, and metoclopramide. Aspirin belongs to a group of medicines known as analgesics (painkillers). It helps to ease the pain you feel during a migraine headache. Metoclopramide is an médicament contre la nausée, also called an anti-emetic. It helps to stop you from feeling sick (nausea).
This medicine is used to treat headache and sickness during an occasional migraine attack. If you have migraines frequently, you should discuss this with your doctor, as there are other medicines available that can help to reduce the number of migraine attacks.
Before taking aspirin and metoclopramide
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you take MigraMax® it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If you are under 18 years of age - MigraMax® must not be taken by anyone under 18 years old.
If you have any allergies, or if you have asthma.
Si vous avez déjà eu un ulcère d'estomac ou duodénal.
If you have epilepsy, Parkinson's disease, or gout.
Si vous avez des problèmes avec le fonctionnement de votre foie ou de vos reins.
If you know you have a problem with your digestive system, such as a blockage or any internal bleeding.
If you have a heart condition or a problem with your thyroid gland.
If you have a blood disorder such as haemophilia, or glucose-6-phosphate dehydrogenase (G6PD) deficiency.
If you have a tumour on your adrenal gland (known as phaeochromocytoma).
If you have ever had an unusual or allergic-type reaction after taking aspirin or a non-steroidal anti-inflammatory drug (NSAID). NSAIDs include ibuprofen, diclofenac, indometacin and naproxen. You should also let your doctor know if you have ever had an allergic reaction to any other medicine.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How to take aspirin and metoclopramide
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about the medicine and it will provide you with a full list of the side-effects which you may experience.
Take MigraMax® exactly as your doctor tells you to. As soon as a migraine starts, stir the contents of one sachet into a small glass of water and drink it straightaway. You can take a further sachet in the same way after two hours if needed. Do not take more than a total of three sachets in any 24-hour period.
If you are able, try to take the sachets with something to eat.
Tirer le meilleur parti de votre traitement
A number of things can trigger migraines in some people. These can include some foods (for example, cheese, chocolate, and red wine), worry, bright sunlight, too much or too little sleep, and skipping meals. If you are not sure if these things trigger a migraine for you, it may help for you to keep a migraine diary. Note down when and where each migraine attack started, what you were doing, and what you had eaten that day. A pattern may emerge and it may be possible for you to avoid some of the things that trigger an attack.
Try to keep any follow-up appointments with your doctor. MigraMax® will only be prescribed for a short period of time. Only take it during a migraine attack.
You will not be prescribed the treatment for longer than three months in total, as this could lead to some serious unwanted effects. If you continue to be troubled with migraines, discuss this with your doctor, as an alternative preparation will be more suitable for you.
It is important that you do not take more than one preparation containing aspirin at a time. Aspirin is an ingredient in some over-the-counter preparations for cold and flu, so before you take any other medicines, check the label to see whether they contain aspirin.
Some people who get frequent migraine attacks are in fact getting medication-induced headache. Medication-induced headache (also called medication-overuse headache) is caused by taking painkillers too often. If you use painkillers on more than two days a week on a regular basis, you may be at risk of this. You should talk with your doctor if you suspect it.
Taking too much aspirin can cause serious problems. If you suspect that you have taken more than the prescribed dose, or if a child accidentally ingests the contents of a sachet, contact your local accident and emergency department for advice immédiatement.
Can aspirin and metoclopramide cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the side-effects associated with MigraMax®. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following become troublesome.
MigraMax® side-effects | Que puis-je faire si je ressens cela ? |
Se sentir étourdi ou somnolent | Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines |
Diarrhée | Buvez beaucoup d'eau pour remplacer les fluides perdus |
Indigestion, stomach upset | Take MigraMax® after a snack if possible |
Distressing muscle or movement disorders affecting the body, face, or eyes | Let your doctor know about this immédiatement |
Breast changes, irregular periods, mood changes, increased risk of bleeding and bruising | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
Important: aspirin can cause allergic reactions; this is more common in people who have asthma. If you have an allergic reaction or develop any breathing difficulties, stop taking MigraMax® and speak with a doctor urgently.
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.
How to store aspirin and metoclopramide
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Can I take MigraMax if I am planning to get pregnant?
If you are trying for a baby, you should inform your doctor before taking MigraMax. They will advise if this medicine is suitable for you during this time.
How long should I wait between doses of MigraMax if my migraine doesn't go away?
You can take a second sachet of MigraMax two hours after the first dose if your migraine symptoms persist. However, you should not take more than three sachets within a 24-hour period.
Are there particular foods or activities that might trigger a migraine that I should be aware of?
Yes, certain things can trigger migraines for some people. These can include specific foods like cheese, chocolate, and red wine, as well as factors like worry, bright sunlight, too much or too little sleep, and skipping meals. Keeping a migraine diary can help identify your personal triggers.
What should I do if I accidentally take more than the recommended dose of MigraMax?
If you suspect you have taken more than the prescribed dose of MigraMax, or if a child accidentally ingests it, you should contact your local accident and emergency department for advice immediately. Remember to take the empty container with you.
What if my migraines are not responding to MigraMax after a while?
MigraMax is prescribed for short-term use during a migraine attack and typically not for longer than three months in total due to potential serious unwanted effects. If you continue to be troubled by migraines, you should discuss this with your doctor, as an alternative treatment might be more suitable for you.
Can MigraMax cause any issues during an operation or dental procedure?
Yes, it is important to inform the person carrying out any operation or dental treatment about all the medicines you are currently taking, including MigraMax.
Lectures complémentaires et références
- Manufacturer's PIL, MigraMax® powder for oral solution; Zentiva Pharma UK Ltd, The electronic Medicines Compendium. Dated December 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Next review due: 22 Oct 2026
23 oct. 2023 | Dernière version

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