Bezafibrate pour l'hyperlipidémie
Bezalip
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 30 août 2022
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Take bezafibrate tablets with or just after a meal.
Some lifestyle changes will also help to reduce your cholesterol level - eat healthy food, stop smoking, increase the exercise you take, and reduce the amount of salt in your diet.
If you develop any unusual aches and pains in your muscles, contact your doctor for advice.
At a glance
Bezafibrate is a medicine used to lower high levels of fats (lipids) in your blood.
High lipid levels can increase the risk of heart disease, stroke, and circulation problems.
Take bezafibrate exactly as prescribed by your doctor, usually with or after a meal.
If you forget a dose, take it when you remember unless it is almost time for your next one.
Tell your doctor if you experience muscle aches or pains, especially in your legs.
Bezafibrate works best when combined with a healthy lifestyle, including diet and exercise.
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About bezafibrate
Type de médicament | A lipid-regulating medicine commonly known as a fibrate |
Utilisé pour | Hyperlipidémie |
Aussi appelé | Bezalip®; Bezalip® Mono |
Disponible sous forme de | Tablets and prolonged-release tablets |
Lipid is another word for fat. Cholesterol and triglycerides are types of lipid. When the concentration of lipids in your blood is too high, it is called hyperlipidémie. Lipids are made naturally in our bodies and are also absorbed from the food we eat. If the levels of lipids are too high, the excess fat is deposited on to the walls of our blood vessels. This can lead to patches like small fatty lumps developing within the lining of some blood vessels. These patches can reduce the flow of blood and lead to heart disease, stroke, and blood circulation problems.
High levels of lipids do not make people feel ill, but they can cause the problems mentioned above if left untreated. By lowering the levels of fats, bezafibrate helps to prevent these long-term heart and circulation problems. Your treatment will be more successful if you also follow the healthy lifestyle advice given by your doctor.
It is likely that you will be prescribed bezafibrate if you have a high triglyceride level. It may also be given for other types of hyperlipidaemia, especially if other medicines (called statins) are not suitable for you.
Before taking bezafibrate
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking bezafibrate it is important that your doctor or pharmacist knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If you have liver, kidney or gallbladder problems.
Si vous avez une glande thyroïde sous-active.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take bezafibrate
Retour au sommaireBefore you start this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about the brand of bezafibrate that you have been given, and a full list of side-effects which are possible from taking it.
Take bezafibrate exactly as your doctor has told you. Your doctor or pharmacist will tell you how often to take the tablets. This will be once daily if you have been given a prolonged-release tablet, and three times daily if not. Your dose will be on the label of the pack to remind you.
Try to take bezafibrate at the same times of day each day, as this will help you to remember to take your doses. Take the tablets with or immediately after a meal.
If you have been given prolonged-release tablets (Bezalip® Mono and Fibrazate® XL brands), it is important that you swallow the tablets whole - do not chew, crush, or break them.
If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose, in which case skip the missed dose. Do not take two doses at the same time to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireEssayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.
Your doctor will give you advice about eating a healthy diet, reducing the amount of salt in your diet, stopping smoking and taking regular exercise. Following this advice will also help you to reduce your risk of developing heart and blood vessel disease.
Treatment with bezafibrate is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
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Can bezafibrate cause problems?
Retour au sommaireEn plus de leurs effets bénéfiques, la plupart des médicaments peuvent provoquer des effets secondaires indésirables, bien que tout le monde ne les ressente pas. Ceux-ci s'améliorent généralement à mesure que votre corps s'adapte au nouveau médicament, mais parlez à votre médecin ou à votre pharmacien si l'un des effets secondaires suivants persiste ou devient gênant.
Bezafibrate side-effects - these affect fewer than 1 in 10 people who take this medicine | Que puis-je faire si je ressens cela ? |
Feeling sick (nausea) or bloated, lack of appetite | Stick to simple, healthy and appetising foods |
Selles molles et liquides (diarrhée) | Buvez beaucoup d'eau pour remplacer les fluides perdus |
Important: if you develop any muscle aches or pains, particularly in your legs, you should tell your doctor about it as soon as possible.
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
How to store bezafibrate
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is hyperlipidaemia?
Hyperlipidaemia is a condition where the concentration of lipids (fats), such as cholesterol and triglycerides, in your blood is too high. This excess fat can deposit on blood vessel walls, forming fatty lumps that reduce blood flow, potentially leading to heart disease, stroke, and circulation problems.
Why is it important to treat high lipid levels if they don't make me feel ill?
Even though high lipid levels don't cause immediate symptoms, if left untreated, the excess fat can build up in your blood vessels over time. This can lead to serious long-term problems such as heart disease, stroke, and issues with blood circulation. Bezafibrate helps prevent these by lowering your fat levels.
When is bezafibrate typically prescribed?
Bezafibrate is most commonly prescribed if you have a high level of triglycerides. It might also be used for other types of hyperlipidaemia, especially if other common medicines, like statins, are not suitable for you.
Should I take bezafibrate with or without food?
You should take your bezafibrate tablets with food or immediately after a meal. This is stated in the instructions for how to take the medicine.
What should I do if I forget to take a dose of bezafibrate?
If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, you should skip the missed dose and continue with your regular schedule. Do not take two doses at once to compensate for a forgotten one.
How long will I need to take bezafibrate?
Treatment with bezafibrate is usually long-term. You should continue taking the tablets exactly as prescribed by your doctor unless they advise you otherwise, such as if you experience an adverse effect.
Can I continue to take other medicines, including herbal remedies, while on bezafibrate?
Before starting bezafibrate, it's very important to inform your doctor or pharmacist about all other medicines you are taking. This includes any you buy without a prescription, as well as herbal and complementary medicines. This is to ensure there are no unsuitable combinations or interactions.
Lectures complémentaires et références
- Summary of medicinal Product Characteristics (SPC), Fibrazate® XL 400 mg Modified Release Tablets; Sandoz Ltd, The electronic Medicines Compendium. Dated September 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 27 fév. 2027
30 août 2022 | Dernière version

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