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Buserelin for men

Suprefact

Buserelin (brand name Suprefact®) is a hormone treatment for men with prostate cancer who have not had surgery to remove the testicles.

Each time you collect your prescription for buserelin, check to make sure the brand name is Suprefact®. This is because there is another brand of buserelin nasal spray available, which is not suitable for you.

Use one spray into each nostril six times each day.

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About buserelin for men

Type de médicament

A gonadorelin analogue

Utilisé pour

Cancer de la prostate

Aussi appelé

Suprefact®

Disponible sous forme de

Injection et spray nasal

Although in many cases cancer de la prostate is slow-growing, in some men it can be more aggressive and spread to other parts of the body. When this happens, there can be a benefit from using a hormone treatment, such as buserelin, which slows the progress of the cancer.

Prostate cancer cells need the male hormone testosterone to grow. Buserelin works by reducing the production of testosterone and this helps to stop the growth of the cancer cells.

Buserelin is also used in some disorders which affect women. There is a separate medicine leaflet called Busereline pour femmes qui donne plus d'informations à ce sujet.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using buserelin it is important that your doctor knows:

  • If you have low moods or are depressed.

  • If you have high blood pressure (hypertension).

  • If you have diabetes (diabetes mellitus).

  • If you have a bone disease such as osteoporosis.

  • Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about buserelin and will provide you with a full list of the side-effects which you could experience.

  • When you start buserelin, you will be given injections every eight hours for the first seven days. For convenience, these injections are likely to be given to you while you are in hospital. On the next day, you will be given a nasal spray to use. You must follow the instructions given to you by your doctor for using the spray, but it is usually recommended that you use one spray into each nostril six times each day as follows:

  • 1st dose before your breakfast.

  • 2nd dose after your breakfast.

  • 3rd dose before your midday meal.

  • 4th dose after your midday meal.

  • 5th dose before your evening meal.

  • 6th dose after your evening meal.

  • Each time you open a new bottle, you will need to attach the nebuliser to the bottle of solution and then 'prime' the spray. You do this by pumping the spray about six or seven times until you see a fine spray produced. Priming fills the nebuliser and tests that the spray is working correctly.

  • It is important that you use this medicine regularly and space the doses out evenly through the day. If you forget to take a dose at your usual time, take it as soon as you remember. If it is almost time for your next dose then skip the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

  • About 1 in 10 men notice that their symptoms (usually pain) become worse for a short while when they first start treatment with buserelin. Your doctor is likely to give you some tablets to take during the first few weeks to help prevent this. If you do experience any increase in pain, this will settle again after a couple of weeks.

  • Please keep your appointments with your doctor so that your progress can be monitored. Your doctor will want you to have regular blood tests to check your hormone levels.

  • Even if you get a cold or your nose feels blocked, you should continue to use the spray as it will still work. If you are using any other nasal sprays (such as decongestants), you should use buserelin spray first, then wait at least 30 minutes after using buserelin before using the other nasal spray.

  • Buserelin can affect your blood sugar levels. If you have diabetes you may need to check your blood glucose more frequently. Your doctor will advise you about this.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with buserelin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common buserelin side-effects (these affect fewer than 1 in 10 men)

Que puis-je faire si je ressens cela ?

Feeling dizzy, tired, or sleepy

Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines pendant que vous êtes affecté

Feeling sick (nausea) or being sick (vomiting), stomach or tummy (abdominal) pain

Optez pour des aliments simples - évitez les repas riches ou épicés

Diarrhée

Buvez beaucoup d'eau pour remplacer les fluides perdus

Constipation

Mangez un régime équilibré et buvez plusieurs verres d'eau chaque jour

Headache, muscle pain and stiffness

Ask your pharmacist to recommend a suitable painkiller

Irritation of your nose or throat, nosebleeds, changes in the way things smell and taste, changes in your weight, feeling nervous or depressed, disturbed sleep, being aware of a fast heartbeat, dry skin, acne, changes in the thickness of your hair

Si l'un de ces éléments devient problématique, parlez-en à votre médecin

Important: In rare cases this medicine may cause a serious allergic reaction. Seek urgent medical attention if you develop a red, itchy skin rash and any difficulties with your breathing, including swelling of the face, lips or tongue. Taking an antihistamine may help slow the reaction whilst you are waiting for treatment.

If you experience any other symptoms which you think may be due to buserelin, please speak with your doctor or pharmacist for further advice.

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  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

  • Each bottle of nasal spray contains one week of treatment. Even if there is some solution left after using the spray for a week, please do not use it. Instead, open a fresh bottle.

Informations importantes sur tous les médicaments

Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sans danger à prendre avec vos autres médicaments.

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

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Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 3 sept. 2027
  • 14 Sept 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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