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Comprimés de capcitabine

You will be prescribed capecitabine tablets by a specialist doctor.

Swallow your doses with a drink of water. They should be taken within 30 minutes of eating a meal.

Please keep your regular clinic appointments so that your doctor can check on your progress. If you think you are getting an infection or if you have a high temperature, please contact your doctor for advice straightaway.

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About capecitabine

Type de médicament

Médicament anticancéreux antimétabolite

Utilisé pour

Treatment of cancers (in adults) such as colon cancer, rectal cancer, stomach cancer, and breast cancer

Disponible en

Tablettes

In cancer, certain cells in the body grow and multiply too fast. As the cancer cells multiply they form a tumour. Anti-cancer medicines like capecitabine work by interfering with the growth of cancer cells, which slows down the growth of the tumour. Capecitabine is prescribed in particular for colon cancer, colorectal cancer, and stomach cancer. It is also sometimes prescribed for breast cancer.

Before taking capecitabine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking capecitabine it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous avez une infection ou si vous vous sentez particulièrement mal.

  • Si vous avez des problèmes avec le fonctionnement de votre foie ou de vos reins.

  • If you have a heart condition or if you have an irregular heartbeat.

  • If you have a problem with your nervous system.

  • Si vous avez trop de sucre dans le sang (diabète sucré).

  • If you have been told by a doctor that the level of any electrolyte (such as calcium, sodium, potassium) in your blood is either too high or too low.

  • If you have been told by a doctor that you lack certain enzymes which help remove medicines from your body.

  • Si vous avez déjà eu une réaction allergique à un médicament.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

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How to take capecitabine

  • Before you start the treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of tablets. These will give you more information about capecitabine and will provide you with a full list of the side-effects which you may experience from taking it.

  • Capecitabine will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your dose will be calculated from your weight and height, so it is important that you take the tablets exactly as your doctor tells you to. There are several strengths of tablet available and your dose may be a combination of the different strengths. It is usual to take the tablets in cycles of two doses every day (morning and evening) for 14 days, followed by a seven-day break. This 21-day cycle is then repeated over a number of months. Your dose will be printed on the label of the pack of tablets to remind you about what the doctor said to you.

  • Swallow the tablets whole with a drink of water. Do not cut, crush or chew the tablets.

  • You should take the tablet within 30 minutes of eating a meal. It will help you to remember to take your doses regularly if you take them after the same meals each day, usually breakfast and dinner.

  • If you forget to take a dose, make sure you remember to take the next dose when it is due and let your doctor know about the missed dose. Do not take two doses at the same time to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with capecitabine.

  • It is important that you do not get pregnant or father a child while you are taking capecitabine. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Many anti-cancer treatments are associated with reduced fertility (particularly in men), so you may also want to ask your doctor for family planning advice if you would like to have children in the future.

  • While you are taking capecitabine and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Capecitabine lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines. For example, you should not take vitamin preparations which contain folic acid.

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Can capecitabine cause problems?

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. While you are taking capecitabine you should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment. The table below contains some of the most common side-effects associated with capecitabine, although not everyone experiences these. You will find a full list in the manufacturer's information leaflet supplied with your tablets. Please let your doctor know if you experience any of the following:

Very common capecitabine side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Sore hands and feet, rash, dry itchy skin

Informez votre médecin de cette situation dès que possible.

Diarrhée

Drink plenty of water so that you don't become lacking in fluid in the body (dehydrated). If you have four bowel movements a day more than what is normal for you, you must let your doctor know as soon as possible, as your dose may need adjusting for a short while

Feeling sick (nausea) or being sick (vomiting), tummy (abdominal) pain, lack of appetite

Mangez des repas simples (évitez les aliments riches ou épicés). Si cela devient gênant, prévenez votre médecin, qui pourra vous prescrire un médicament anti-maladie.

Feeling feverish, infections (due to changes in the number of your blood cells)

Informez votre médecin de cette situation dès que possible.

Feeling tired or weak

Ne pas conduire et ne pas utiliser d'outils ou de machines pendant la durée de l'affection.

Bouche sèche ou douloureuse

Try chewing sugar-free gum or sucking sugar-free sweets. Also, let your doctor know about this, as there are preparations available which may be of help

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

How to store capecitabine

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Prochaine révision prévue : 9 octobre 2027
  • 5 Oct 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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