Préparations cutanées à la clindamycine pour l'acné
Dalacin T, Zindaclin
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 18 mai 2023
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Clindamycin is an antibiotic - to treat acne, it is applied to the skin as a lotion, solution, or gel.
Apply the preparation to all of the affected area of skin, not just to individual spots.
The most common side-effect is mild skin irritation.
En un coup d'œil
Clindamycin is an antibiotic skin preparation used to treat acne.
It is available as a solution, lotion, or gel.
You should apply it exactly as your doctor tells you, usually once or twice daily.
Common side effects include skin irritation, itching, dryness, or oiliness.
Consult your doctor if you experience diarrhoea while using this preparation.
About clindamycin skin preparations
Type de médicament | An antibiotic skin preparation |
Utilisé pour | Acné |
Aussi appelé | Dalacin T®; Zindaclin®; Duac® Once Daily (clindamycin with peroxyde de benzoyle); Treclin® (clindamycin with la trétinoïne) |
Disponible sous forme de | Solution, lotion and gel |
Acné is the common cause of spots. Most people with acne are aged between 12 and 25 years, but some older and younger people are affected too. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Tiny pores on your skin allow the sebum to come on to the surface of your skin. In acne, some of these pores become blocked, causing inflamed spots.
Antibiotics like clindamycin, work by stopping bacteria that can contribute to acne from multiplying. One brand of clindamycin (Duac® Once Daily gel) also contains peroxyde de benzoyle, which helps to unplug blocked pores. Clindamycin is also available in combination with la trétinoïne in a gel called Treclin®.
Clindamycin is also available as capsules to take by mouth, and as a cream for vaginal infection. These are used for other conditions, not acne. There are two separate medicine leaflets available which provide more information about these, called Capsules de clindamycine pour infection et Crème de clindamycine pour la vaginose bactérienne.
Before using clindamycin skin preparations
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using clindamycin on your skin, it is important that your doctor knows:
If you are pregnant or breastfeeding. (Although using clindamycin lotion is not known to be harmful to an unborn baby, you should let your doctor know if you think you are pregnant.)
If you have any bowel problems which cause you to have diarrhoea.
If you have ever had an allergic reaction to a medicine or a skin preparation.
How to use clindamycin skin preparations
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about clindamycin, and it will also explain how to use the preparation you have been prescribed.
Apply the preparation exactly as your doctor tells you to. Wash and gently dry your skin, and then apply a thin layer to the whole of the area where your spots occur. The label on the pack will tell you how many times a day to use the preparation. Some clindamycin skin preparations are used once each day, others are used twice a day. Wash your hands well after using it.
Dalacin T® topical solution contains a small amount of alcohol which can cause stinging if it gets into grazes, or on to sensitive areas of skin. If you are using this brand of clindamycin, try to avoid getting it on areas of your skin in or around your nostrils, your eyes and your mouth.
Tirer le meilleur parti de votre traitement
Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. A full course of treatment may last for several months.
It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water may worsen acne. Do not wash more than you normally do. You cannot clean off blackheads.
During your treatment your doctor may ask you to use another (non-antibiotic) skin preparation from time to time. It is important that you follow your doctor's advice, as this is to help prevent your spots from becoming resistant to treatment.
Can clindamycin skin preparations cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with clindamycin when used on the skin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common clindamycin side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Skin irritation, itching, dryness or oiliness | Stop using the preparation for a day or so to allow your skin to recover. These effects usually reduce as your skin gets used to the preparation, but if they continue or become troublesome, you should speak with your doctor |
Less common clindamycin side-effects (these affect fewer than 1 in 100 people) | Que puis-je faire si je ressens cela ? |
Diarrhée | Contact your doctor for further advice before applying any more of the preparation |
If you experience any other symptoms which you think may be due to the preparation, speak with your doctor or pharmacist.
How to store clindamycin skin preparations
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
This preparation is for external use only. If someone swallows some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui réalise le traitement des médicaments que vous prenez ou utilisez.
This preparation is for you. Never give it to other people, even if their condition appears to be the same as yours.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
If you have any questions about this preparation, ask your pharmacist for further advice.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Are there different forms of clindamycin for acne?
Yes, clindamycin for acne is available as a solution, lotion, and gel. It can also be found in combination preparations, such as Duac® Once Daily gel, which includes benzoyl peroxide, and Treclin® gel, which contains tretinoin.
How do clindamycin skin preparations help with acne?
Clindamycin is an antibiotic that works by stopping the proliferation of bacteria that contribute to acne. Some combination products, like Duac® Once Daily gel, also contain ingredients (benzoyl peroxide) that help to unblock pores.
What should I do if I am pregnant or breastfeeding and considering using clindamycin skin preparations?
It's important to inform your doctor if you are pregnant or breastfeeding. While using clindamycin lotion is not known to be harmful to an unborn baby, your doctor needs to be aware of your situation.
When should I apply clindamycin skin preparations?
You should apply the preparation exactly as instructed by your doctor. Typically, you wash and gently dry your skin, then apply a thin layer to the entire area affected by spots. The frequency of application (once or twice daily) will be indicated on the product label and by your doctor. Always remember to wash your hands well after applying it.
Can clindamycin skin preparations be used for other types of infections?
While clindamycin is an antibiotic, the skin preparations discussed are specifically for acne. Clindamycin also comes in capsules for oral use and a cream for vaginal infections, but these forms are used for different conditions and not for acne.
Lectures complémentaires et références
- Manufacturer's PIL, Dalacin® T Topical Solution/Topical Lotion; Pfizer Limited, The electronic Medicines Compendium. Dated February 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 17 nov. 2027
18 mai 2023 | Dernière version

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