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Colestipol - un médicament hypolipidémiant

Colestid

Note de l'auteur clinique Michael Stewart 05/01/2024: Colestid® sachets were discontinued in the United Kingdom in January 2023. At the time of review there are no licensed products containing colestipol available in the UK. Colestipol tablets and sachets may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Take each sachet of colestipol granules mixed into at least 100 ml of liquid or soft food such as fruit juice, skimmed milk, soup, or yoghurt.

Avoid taking any other medicines at the same time as colestipol. Either take your other medicines one hour before colestipol, or wait until 4-6 hours afterwards.

The main side-effect of colestipol is constipation.

En un coup d'œil

  • Colestipol is a medicine used to lower high levels of cholesterol and other fats in your blood.

  • It works by preventing bile acids in your digestive system from being reabsorbed by your body.

  • Take colestipol exactly as prescribed by your doctor, usually mixed with water or other liquids/foods.

  • Avoid taking other medicines at the same time as colestipol to prevent issues with absorption.

  • Common side-effects can include constipation and stomach pain.

  • Tell your doctor if you are pregnant, breastfeeding, or taking other medicines before starting colestipol.

About colestipol

Type de médicament

A bile acid binder (sequestrant)

Utilisé pour

Lowering cholesterol and other lipids

Aussi appelé

Colestid® (Discontinued in UK)

Disponible sous forme de

Tablets and sachets of granules

Colestipol is available as sachets of granules which work in the body as a bile acid sequestrant. This means that it binds to bile acids in your digestive system. It prevents the bile acids from being recycled (reabsorbed) into your body. This action can be useful for people who have higher than normal levels of lipids in their blood.

Lipid is another word for fat. Cholesterol is a type of lipid. Lipids are easily stored in your body and serve as a source of energy. They are made naturally in your body from the food you eat. When the concentration of lipids in your blood is too high, it is called hyperlipidaemia. By taking colestipol, it prevents your bile acids from being reabsorbed and, as a consequence, your liver has to make more bile acids. It does this by using certain lipids from your blood. This lowers the amount of lipids in your blood and reduces your risk of heart and blood vessel disease.

Before taking colestipol

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking colestipol it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

How to take colestipol

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about colestipol and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take the sachets exactly as your doctor tells you to. It is usual to be prescribed one sachet to take once or twice each day to begin with. Depending upon your symptoms, your doctor may slowly increase the number of sachets until you are taking up to six sachets daily.

  • The granules from each sachet should be added to at least 100 ml of water. If you prefer, you can also mix colestipol with skimmed milk, soup, fruit juice, yoghurt or fruit smoothies. The granules do not dissolve well and can have a 'bitty' texture. You will notice this less if you mix the granules with soft foods rather than thin liquids, or alternatively if you prepare your dose a little in advance and allow it to stand for a while. Do not take the granules dry or without mixing them into about 100 ml of drink/food first. Colestipol sachets are also available pre-flavoured with orange and vanilla and with an artificial sweetener in a brand called Colestid® Orange.

  • If you forget to take a dose, take it as soon as you remember. Try to take the correct number of sachets each day, but do not take two doses together to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.

  • Avoid taking any other medicines at the same time as you take colestipol because it can stop the other medicines from being absorbed by your body. Either take your other medicines at least one hour before you take colestipol, or wait until 4-6 hours after taking colestipol before you take the other medicines. If you have any problems planning when to take your medicines, speak with your doctor or pharmacist for advice.

  • Treatment with colestipol is often long-term. Continue to take it unless you are advised otherwise.

  • Taking colestipol over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D, E and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.

  • Your doctor may give you advice about lifestyle changes that could help you get the most out of your treatment. This may include reducing the amount of salt in your diet, stopping smoking, losing weight, reducing the amount of alcohol you drink, and taking regular exercise. Following this advice will help you to reduce your risk of developing heart and blood vessel disease in the future.

  • Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take.

Can colestipol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with colestipol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common colestipol side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Constipation

Try to eat a well-balanced diet and drink several glasses of water each day. If it becomes troublesome, speak with your doctor

Abdominal (tummy) pain or discomfort

Optez pour des repas simples - évitez les aliments riches ou épicés

Migraine, headache

Buvez beaucoup d'eau et demandez à un pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin

Common colestipol side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Feeling sick (nausea) or being sick (vomiting), indigestion, bloated feeling, wind (flatulence)

Optez pour des repas simples - évitez les aliments riches ou épicés

Bleeding haemorrhoids (piles), blood in your stools

This may be related to constipation. If you notice any blood in your stools you should let your doctor know straightaway

Diarrhée

Drink plenty of water to replace the fluids lost

Joint or muscle aches and pains, back pain

Ask a pharmacist to recommend a suitable painkiller. If the pain continues, let your doctor know

Éruption cutanée

Ask a pharmacist to recommend a suitable antihistamine. If the problem continues, let your doctor know

Fatigue (épuisement)

If this becomes a problem, let your doctor know

If you experience any other symptoms which you think may be due to your medicine, speak with your doctor or pharmacist for further advice.

How to store colestipol

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

MHRA - Signaler des réactions indésirables

Signalez les effets secondaires suspectés des médicaments, vaccins, cigarettes électroniques, incidents liés aux dispositifs médicaux, produits défectueux ou falsifiés (contrefaits) à l'Agence de Régulation des Médicaments et Produits de Santé pour garantir une utilisation sûre et efficace.

vérificateur de symptômes

Vous n'êtes pas sûr de mélanger des médicaments ?

Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Questions fréquemment posées

Can I take colestipol with other liquids besides water?

Yes, you can mix colestipol granules with other liquids like skimmed milk, soup, fruit juice, or fruit smoothies. You can also mix them with soft foods like yoghurt. The granules don't dissolve easily, so mixing them with soft foods or preparing your dose in advance and letting it sit can help improve the texture.

How long will I need to take colestipol?

Treatment with colestipol is often long-term. You should continue to take it unless your doctor advises you otherwise.

What should I do if I find the texture of colestipol granules unpleasant?

The granules do not dissolve well and can have a 'bitty' texture. You may find this less noticeable if you mix them with soft foods rather than thin liquids, or if you prepare your dose a little in advance and allow it to stand for a while. Colestipol sachets are also available pre-flavoured with orange and vanilla, and with an artificial sweetener under the brand name Colestid® Orange.

Are there any specific lifestyle changes I should consider while taking colestipol?

Your doctor may recommend lifestyle changes to help you get the most from your treatment and further reduce your risk of heart and blood vessel disease. These might include reducing salt intake, stopping smoking, losing weight, reducing alcohol consumption, and getting regular exercise.

What if I accidentally swallow the granules dry?

You should not take the granules dry or without mixing them into at least 100 ml of drink or food first.

Can colestipol affect my vitamins?

Taking colestipol over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D, E, and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.

Lectures complémentaires et références

À propos de l'auteurVoir la biographie complète

Image de l'auteur

Michael Stewart, MRPharmS

Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien

BPharm (Hons), MRPharmS

Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.

À propos du critique

Image de l'auteur

Sid Dajani

Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 9 janv. 2027
  • 10 janv. 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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