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Colestipol - un médicament hypolipidémiant

Colestid

Clinical author's note Michael Stewart 05/01/2024: Colestid® sachets were discontinued in the United Kingdom in January 2023. At the time of review there are no licensed products containing colestipol available in the UK. Colestipol tablets and sachets may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Take each sachet of colestipol granules mixed into at least 100 ml of liquid or soft food such as fruit juice, skimmed milk, soup, or yoghurt.

Avoid taking any other medicines at the same time as colestipol. Either take your other medicines one hour before colestipol, or wait until 4-6 hours afterwards.

The main side-effect of colestipol is constipation.

Poursuivre la lecture ci-dessous

About colestipol

Type de médicament

A bile acid binder (sequestrant)

Utilisé pour

Lowering cholesterol and other lipids

Également appelé

Colestid® (Discontinued in UK)

Disponible en

Tablets and sachets of granules

Colestipol is available as sachets of granules which work in the body as a bile acid sequestrant. This means that it binds to bile acids in your digestive system. It prevents the bile acids from being recycled (reabsorbed) into your body. This action can be useful for people who have higher than normal levels of lipids in their blood.

Lipid is another word for fat. Cholesterol is a type of lipid. Lipids are easily stored in your body and serve as a source of energy. They are made naturally in your body from the food you eat. When the concentration of lipids in your blood is too high, it is called hyperlipidaemia. By taking colestipol, it prevents your bile acids from being reabsorbed and, as a consequence, your liver has to make more bile acids. It does this by using certain lipids from your blood. This lowers the amount of lipids in your blood and reduces your risk of heart and blood vessel disease.

Before taking colestipol

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking colestipol it is important that your doctor knows:

  • Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

Poursuivre la lecture ci-dessous

How to take colestipol

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about colestipol and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take the sachets exactly as your doctor tells you to. It is usual to be prescribed one sachet to take once or twice each day to begin with. Depending upon your symptoms, your doctor may slowly increase the number of sachets until you are taking up to six sachets daily.

  • The granules from each sachet should be added to at least 100 ml of water. If you prefer, you can also mix colestipol with skimmed milk, soup, fruit juice, yoghurt or fruit smoothies. The granules do not dissolve well and can have a 'bitty' texture. You will notice this less if you mix the granules with soft foods rather than thin liquids, or alternatively if you prepare your dose a little in advance and allow it to stand for a while. Do not take the granules dry or without mixing them into about 100 ml of drink/food first. Colestipol sachets are also available pre-flavoured with orange and vanilla and with an artificial sweetener in a brand called Colestid® Orange.

  • If you forget to take a dose, take it as soon as you remember. Try to take the correct number of sachets each day, but do not take two doses together to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Essayez de vous rendre à vos rendez-vous réguliers avec votre médecin. Il pourra ainsi vérifier vos progrès. Il se peut que vous deviez faire des analyses de sang de temps en temps.

  • Avoid taking any other medicines at the same time as you take colestipol because it can stop the other medicines from being absorbed by your body. Either take your other medicines at least one hour before you take colestipol, or wait until 4-6 hours after taking colestipol before you take the other medicines. If you have any problems planning when to take your medicines, speak with your doctor or pharmacist for advice.

  • Treatment with colestipol is often long-term. Continue to take it unless you are advised otherwise.

  • Taking colestipol over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D, E and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.

  • Your doctor may give you advice about lifestyle changes that could help you get the most out of your treatment. This may include reducing the amount of salt in your diet, stopping smoking, losing weight, reducing the amount of alcohol you drink, and taking regular exercise. Following this advice will help you to reduce your risk of developing heart and blood vessel disease in the future.

  • Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take.

Poursuivre la lecture ci-dessous

Can colestipol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with colestipol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common colestipol side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Constipation

Essayez d'avoir une alimentation équilibrée et buvez plusieurs verres d'eau par jour. Si cela devient gênant, parlez-en à votre médecin

Abdominal (tummy) pain or discomfort

S'en tenir à des repas simples - éviter les aliments riches ou épicés

Migraine, headache

Buvez beaucoup d'eau et demandez à un pharmacien de vous recommander un analgésique adapté. Si les maux de tête persistent, prévenez votre médecin

Common colestipol side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Feeling sick (nausea) or being sick (vomiting), indigestion, bloated feeling, wind (flatulence)

S'en tenir à des repas simples - éviter les aliments riches ou épicés

Bleeding haemorrhoids (piles), blood in your stools

This may be related to constipation. If you notice any blood in your stools you should let your doctor know straightaway

Diarrhée

Drink plenty of water to replace the fluids lost

Joint or muscle aches and pains, back pain

Ask a pharmacist to recommend a suitable painkiller. If the pain continues, let your doctor know

Éruption cutanée

Ask a pharmacist to recommend a suitable antihistamine. If the problem continues, let your doctor know

Fatigue (fatigue)

If this becomes a problem, let your doctor know

If you experience any other symptoms which you think may be due to your medicine, speak with your doctor or pharmacist for further advice.

How to store colestipol

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

MHRA - Déclaration des effets indésirables

Signaler à la Medicines and Healthcare products Regulatory Agency les effets secondaires suspectés des médicaments, des vaccins, des e-cigarettes, les incidents liés aux dispositifs médicaux, les produits défectueux ou falsifiés (faux), afin de garantir une utilisation sûre et efficace.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Date de la prochaine révision : 9 janvier 2027
  • 10 Jan 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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