Dompéridone pour le mal des transports
Motilium
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 4 juil. 2023
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Domperidone helps to prevent you from feeling sick (nausea) or being sick (vomiting). It is recommended for short-term use only.
Domperidone may be associated with an increased risk of heart rhythm disorder, particularly in older people. If you faint or feel that your heart is beating quickly, you must speak with your doctor as soon as possible.
At a glance
Domperidone is an anti-sickness medicine used to relieve nausea and vomiting.
It works by speeding up the movement of food through your digestive system.
It is for adults and children over 12 years of age and used for short periods.
Take it about half an hour before meals, up to three times a day.
Do not take for longer than seven days and do not take more than three doses in 24 hours.
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About domperidone
Type de médicament | Anti-emetic |
Utilisé pour | Nausea and vomiting in adults and in children over 12 years of age |
Aussi appelé | Motilium® |
Disponible sous forme de | Comprimés et médicaments liquides oraux |
Domperidone is used to relieve feelings of sickness (nausea) or being sick (vomiting). Feeling sick can be a common symptom, but it may be due to a number of different causes. You will only be recommended an anti-emetic like domperidone if the cause of your sickness is known.
Domperidone works by helping to move the food in your stomach through your digestive system more quickly. This helps to stop you from feeling sick.
Before taking domperidone
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking domperidone it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If it is for a child under 12 years of age.
Si vous avez des problèmes avec votre foie ou vos reins.
If you have problems with your heart or if you have been told you have an irregular heart rhythm.
If you know you have any problems with your digestive system, such as a blockage or any internal bleeding.
If you have a tumour on your pituitary gland, known as a prolactinoma.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take domperidone
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about domperidone and will provide you with a full list of the side-effects which you may experience from taking it.
Take domperidone exactly as your doctor tells you to. The dose for adults and for young people aged 12 years or over is 10 mg (one tablet) up to three times a day. Do not take more than three doses in any 24-hour period.
Take your doses about half an hour before meals. If you take domperidone after a meal, it will still work, but it may take longer to have an effect.
Domperidone should be taken for a short period of time only. Your treatment will last no longer than seven days.
Can domperidone cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with domperidone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following become troublesome.
Domperidone side-effects | Que puis-je faire si je ressens cela ? |
Bouche sèche | Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre |
Fainting, a feeling of fast heartbeats (palpitations) | Speak with a doctor straightaway |
Feeling anxious, feeling sleepy or weak, headaches, diarrhoea | If troublesome, speak with a doctor or pharmacist for advice |
Breast swelling or tenderness, menstrual changes, unusual production of breast milk, itchy skin rash | Let your doctor know about any of these |
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.
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How to store domperidone
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.
Si vous devez subir une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez jamais de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
How does domperidone actually stop me from feeling sick?
Domperidone works by helping your stomach to move food through your digestive system more quickly. This increased movement helps to reduce feelings of sickness.
Can domperidone be given to young children under 12 years old?
Domperidone is used for adults and children over 12 years of age. If it is for a child under 12, this needs to be discussed with a doctor.
What should I do if I forget to take a dose of domperidone?
The article states to take domperidone exactly as your doctor tells you to, and not to exceed three doses in a 24-hour period. It's best to follow your doctor's specific instructions for missed doses, but typically you would take it about half an hour before your next meal.
How long will I be taking domperidone for?
Domperidone is intended for short-term use only. Your treatment with this medicine will not last longer than seven days.
Are there any warning signs I should look out for that mean I need to contact a doctor straight away?
Yes, you should speak with a doctor straightaway if you experience fainting or a feeling of fast heartbeats (palpitations) while taking domperidone.
Who should not take domperidone?
Domperidone might not be suitable for you if you have problems with your liver, kidneys, or heart, especially an irregular heart rhythm. It's also not recommended if you have certain digestive system issues like a blockage or internal bleeding, or if you have a tumour on your pituitary gland called a prolactinoma. Your doctor needs to know if any of these apply to you before you start taking it.
Can I take domperidone alongside other medications or herbal remedies?
It's important to let your doctor know about all other medicines you are taking, including those bought without a prescription, as well as any herbal or complementary medicines. This is because some medicines are not suitable to be taken together, or may require extra care.
What if my sickness is due to an unknown cause?
You will only be recommended an anti-emetic like domperidone if the cause of your sickness is known. If the cause is unknown, domperidone would not be prescribed.
Lectures complémentaires et références
- Manufacturer's PIL, Motilium® 10 mg Film-Coated Tablets; Zentiva, The electronic Medicines Compendium. Dated April 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 3 juil. 2026
4 juil. 2023 | Dernière version

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