Comprimés de Flupentixol
Depixol, Fluanxol
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 29 mai 2023
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Flupentixol is prescribed to treat two different conditions. The brand called Depixol® is given to relieve symptoms of schizophrenia, and the brand called Fluanxol® is prescribed for depression. Ask your doctor if you are unsure why it has been prescribed for you.
It may slow your reactions and make you feel drowsy. If this happens, do not drive and do not use tools or machines.
Gardez vos rendez-vous réguliers avec votre médecin. Cela permet de vérifier vos progrès.
En un coup d'œil
Flupentixol is a medicine used to treat schizophrenia, other psychoses, and depression.
It is available as tablets and sometimes given as an injection.
Take your tablets exactly as prescribed, usually once or twice daily, before 4 pm.
Do not stop taking flupentixol suddenly without speaking to your doctor.
Common side-effects include dizziness, headache, dry mouth, and shakiness.
Contact your doctor immediately if you have muscle stiffness, high temperature, confusion, fast heartbeat, and sweating.
Alcohol can increase side-effects; ask your doctor for advice.
About flupentixol
Type de médicament | A thioxanthene medicine |
Utilisé pour | Schizophrenia and other psychoses; depression |
Aussi appelé | Depixol® (for psychoses); Fluanxol® (for depression) |
Disponible sous forme de | Comprimés |
The brand of flupentixol called Depixol® is given to relieve the symptoms of la schizophrénie and other similar mental health problems which affect the way you think, feel or behave. These problems are called psychoses. You may hear, see or sense things that are not there, or believe things that are not true, or feel unusually suspicious. Although the exact cause of psychoses is not known, it is thought to be associated with an altered balance of certain chemicals (neurotransmitters) in the brain. Flupentixol works by changing the balance of these chemicals. Taking flupentixol tablets will help relieve some of your symptoms, and will also help to prevent recurring episodes.
The brand of flupentixol called Fluanxol® is prescribed for people with dépression. The symptoms of depression can include low mood, poor sleep, and poor concentration. These are often eased by taking an antidepressant such as flupentixol.
Flupentixol is sometimes given as an injection rather than as tablets. For more information on this please see our medicine leaflet called 'Injection à action prolongée de flupentixol'.
Before taking flupentixol
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking flupentixol it is important that your doctor knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous avez une maladie cardiaque ou une maladie des vaisseaux sanguins.
If you have liver, kidney, thyroid, or prostate problems.
Si vous avez des problèmes respiratoires.
If you have any of the following: epilepsy, diabetes, Parkinson's disease, raised pressure in your eye (glaucoma), or myasthenia gravis, a condition which causes muscle weakness.
Si vous avez déjà eu un jaunissement de la peau ou du blanc des yeux (jaunisse) ou un trouble sanguin.
If you have a tumour on your adrenal gland, a condition called phaeochromocytoma.
Si vous avez une maladie héréditaire rare appelée porphyrie.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
How to take flupentixol
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about the brand of flupentixol which you have been prescribed. It will also provide a full list of the side-effects which you may experience from taking the tablets.
Your dose will depend upon the reason you have been prescribed flupentixol, so take the tablets exactly as your doctor tells you to. As a guide, the tablets are usually prescribed to be taken once or twice daily. Try to get into the habit of taking your doses at the same times each day, as this will help you to avoid missing any. You can take flupentixol tablets before or after food.
Although flupentixol may make you feel drowsy, it can also have a stimulating effect in some people. Because of this, it is better to take your doses during the day before 4 pm, rather than in the evening.
Si vous oubliez de prendre une dose, prenez-la dès que vous vous en souvenez, sauf s'il est presque l'heure de votre prochaine dose, auquel cas laissez de côté la dose oubliée. Ne prenez pas deux doses ensemble pour compenser une dose oubliée.
Tirer le meilleur parti de votre traitement
Keep your regular doctor's appointments so your progress can be checked. You may need to have some tests from time to time.
If you have been prescribed flupentixol for schizophrenia, treatment is usually long-term. Keep taking the tablets until your doctor tells you otherwise. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually if a change in your treatment becomes necessary.
If you have been prescribed flupentixol for depression, you may feel that it is not working for you straightaway. It can take a few days after starting treatment before the effect begins to build up, and 2-4 weeks before you feel the full benefit. Do not stop taking the tablets after a week or two, mistakenly thinking the medicine is not helping. You should expect that a course of treatment will last for several months after your symptoms have eased. This is normal and helps to prevent your symptoms from recurring.
If you drink alcohol, ask your doctor for advice about drinking while you are on flupentixol. Alcohol will increase the chance that you experience side-effects and is unlikely to be recommended for you.
Suicidal thoughts may be associated with depression and the medicines used to treat it. You may be particularly at risk of such thoughts early in the treatment for depression and after any dosage changes. You must tell your doctor straightaway if you have any thoughts of harming yourself.
If you have diabetes check your blood sugar (glucose) levels regularly, as flupentixol can affect the levels of sugar in your blood.
Flupentixol may cause your skin to become more sensitive to sunlight than normal. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
If you are having an operation, tell the person carrying out the treatment which medicines you are taking. This is important because flupentixol may interfere with the anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable to take with flupentixol.
Can flupentixol cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with flupentixol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Flupentixol side-effects | Que puis-je faire si je ressens cela ? |
Feeling dizzy or sleepy, blurred vision, slowed reaction time | Si cela se produit, ne conduisez pas et n'utilisez pas d'outils ou de machines. Ne buvez pas d'alcool |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin |
Bouche sèche | Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre |
Feeling shaky or restless, unusual or uncontrollable muscle movements | Speak with your doctor as soon as possible about any of these. Your treatment may need adjusting |
Changes in weight, difficulty sleeping, mood changes, reduced sex drive, feeling sick (nausea), breast enlargement, production of breast milk, menstrual problems, fast heartbeats, constipation or diarrhoea, difficulty passing urine | Discutez-en avec votre médecin si l'un d'eux devient gênant |
Important: if you experience symptoms such as muscle stiffness, a very high temperature, feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These may be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
How to store flupentixol
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
How long will I need to take flupentixol?
If you have been prescribed flupentixol for schizophrenia, treatment is usually long-term. You should continue taking the tablets until your doctor advises you to stop. For depression, a course of treatment will typically last for several months after your symptoms have improved to help prevent them from returning.
Can flupentixol make me more sensitive to the sun?
Yes, flupentixol may cause your skin to become more sensitive to sunlight than usual. It is recommended to use a sunscreen that protects against UVA light and has an SPF of at least 15, especially when in strong sunlight or until you understand how your skin reacts. You should also avoid using sunbeds.
What should I do if I think I've taken too much flupentixol?
If you suspect that you or someone else might have taken an overdose of flupentixol, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
Should I tell other healthcare providers that I am taking flupentixol?
Yes, it is important to inform any healthcare professional, such as a surgeon or dentist, that you are taking flupentixol if you are having an operation or any other treatment. This is because flupentixol can potentially interact with the anaesthetic you receive.
Can I drink alcohol while taking flupentixol?
You should ask your doctor for advice about drinking alcohol while you are on flupentixol. Alcohol can increase the likelihood of experiencing side-effects and is generally not recommended.
What if my depression symptoms get worse or I have thoughts of harming myself while on flupentixol?
Suicidal thoughts can be associated with depression and the medicines used to treat it. You might be particularly at risk of such thoughts at the beginning of treatment for depression or after any changes in dosage. It is crucial to tell your doctor straightaway if you have any thoughts of harming yourself.
Lectures complémentaires et références
- Manufacturer's PIL, Fluanxol® 0.5 mg and 1 mg Tablets; Lundbeck Limited, The electronic Medicines Compendium. Dated January 2021.
- Manufacturer's PIL, Depixol® 3 mg Tablets; Lundbeck Limited, The electronic Medicines Compendium. Dated January 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 28 nov. 2027
29 mai 2023 | Dernière version

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