Hydralazine pour l'hypertension artérielle
Apresoline
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour le 12 décembre 2022
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Hydralazine is used to control high blood pressure (hypertension).
Treatment with hydralazine is usually long-term.
The most common side-effects are headaches and being aware of your heartbeat.
Dans cet article :
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About hydralazine
Type de médicament | A vasodilator antihypertensive medicine |
Utilisé pour | The treatment of high blood pressure |
Également appelé | Apresoline® |
Disponible en | Tablettes |
Although many people with high blood pressure (hypertension) do not feel unwell, it is still important that high blood pressure be treated. If left untreated, high blood pressure is a risk factor that can increase your chance of developing heart disease, a stroke, and other serious conditions. Hydralazine will be prescribed alongside other medicines to control high blood pressure.
Hydralazine works by relaxing the muscles in the walls of your blood vessels. This means that your blood vessels widen, which reduces your blood pressure and allows blood and oxygen to circulate more freely around your body. Hydralazine will only be prescribed for you if other treatments are not suitable or effective, as it can increase the amount of water and salt in your body and can increase your heart rate. The other medicines you are prescribed to take alongside it will help to control these side-effects.
Hydralazine is occasionally prescribed by hospital doctors for other heart conditions. If you have been prescribed it for a reason other than high blood pressure, speak with your doctor if you have any questions about your treatment.
Before taking hydralazine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking hydralazine it is important that your doctor knows:
If you have a condition called systemic lupus erythematosus. This is an inflammatory condition also called lupus, or SLE.
Si vous avez des problèmes de fonctionnement du foie ou des reins.
If you have a problem with your blood vessels, such as coronary artery disease or cerebrovascular disease.
if you have a heart condition or have recently had a heart attack.
Si vous êtes enceinte ou si vous allaitez.
Si vous êtes atteint d'une maladie sanguine héréditaire rare appelée porphyrie.
Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take hydralazine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about hydralazine and will provide you with a full list of the side-effects which you could experience from taking the tablets.
Take hydralazine exactly as your doctor tells you to. It is usual to take one tablet twice a day. Try to take your doses at similar times of day each day, as this will help you to remember to take them regularly. There are two strengths of hydralazine tablet - it is usual to take the 25 mg strength tablet to begin with, but this may later be increased to the higher 50 mg strength tablet. Increasing your dose gradually allows your doctor to make sure that you have the dose that best helps your condition, but also keeps unwanted side-effects to a minimum.
Swallow the tablet whole with a drink of water. You can take hydralazine either with or without food.
If you forget to take a dose at your usual time, take it as soon as you remember unless your next dose is due. If your next dose is due then take the dose which is due but leave out the forgotten one. Do not take two doses together to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood pressure measurements, and also some blood and urine tests from time to time.
Your doctor will advise you on what lifestyle changes you can make to help your condition. These could include losing weight if you are overweight, taking regular physical activity, eating a healthy diet, cutting back on the amount of alcohol you drink, stopping smoking, and reducing the amount of salt in your meals and caffeine in your drinks. It is important that you follow any advice you are given.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because some medicines (particularly some anti-inflammatory painkillers) can interfere with the way hydralazine works.
Treatment with hydralazine is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking hydralazine. This is because some anaesthetics can affect your blood pressure.
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Can hydralazine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with hydralazine. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Très fréquente hydralazine side-effects (ces maladies touchent plus d'une personne sur dix) | Que puis-je faire si je suis confronté à cette situation ? |
Maux de tête | Buvez beaucoup d'eau et demandez à votre pharmacien de vous recommander un analgésique adapté. Si les maux de tête persistent, consultez votre médecin |
A fast heartbeat, the sensation of having a 'thumping heart' (palpitations) | Si vous êtes inquiet, parlez-en à votre médecin |
Communs hydralazine side-effects (ces maladies touchent moins d'une personne sur dix) | Que puis-je faire si je suis confronté à cette situation ? |
Feeling flushed, swollen feet or ankles, chest pain | If any of these symptoms continue or cause you concern, speak with your doctor |
Sensation de vertige | If this happens, sit down for a while until you feel better. Do not drive and do not use tools or machines while affected. Do not drink alcohol |
Se sentir malade (nausées) ou être malade (vomissements), diarrhée | Eat simple meals and drink plenty of water to replace lost fluids |
Joint or muscle pain | Speak with your doctor about this as soon as possible. It may be an early sign of systemic lupus erythematosus-like syndrome |
Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.
How to store hydralazine
Conservez tous les médicaments hors de la vue et de la portée des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne conservez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Hydralazine Tablets 25 mg and 50 mg; Accord-UK Ltd, The electronic Medicines Compendium. Dated October 2021.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Date limite de la prochaine révision : 11 décembre 2025
12 Dec 2022 | Dernière version

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