Gélules d'idarubicine
Zavedos
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour le 19 juin 2023
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Swallow idarubicin capsules whole with a drink of water - do not bite, chew or suck the capsules.
Idarubicin may colour your urine red. This is nothing to worry about and will disappear after a day or two.
Respectez vos rendez-vous réguliers avec votre médecin ou l'hôpital. Vous devrez subir des analyses de sang et des examens fréquents.
The most common side-effects are diarrhoea, feeling sick (nausea), sore mouth, and an increased risk of infection.
Dans cet article :
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About idarubicin
Type de médicament | An anthracycline chemotherapy medicine |
Utilisé pour | Treatment of leukaemia and breast cancer |
Également appelé | Zavedos® |
Disponible en | Capsules and injection |
Idarubicin is used to treat some cancers. It is given in particular to treat leukaemia, which is cancer of white blood cells. It is also given for breast cancer if other treatments have not proved effective. It can be used alone or alongside other medicines for the treatment of cancer.
In cancer, certain cells in the body grow and multiply too fast. Chemotherapy (anti-cancer) medicines like idarubicin work by preventing the growth and division of cells, and this reduces the number of cancer cells your body makes. Idarubicin is usually given as an injection but it can also be taken by mouth in the form of capsules. This leaflet provides information about idarubicin capsules.
Before taking idarubicin
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking idarubicin it is important that your doctor or pharmacist knows:
Si vous êtes enceinte ou si vous allaitez.
Si vous avez des problèmes de fonctionnement du foie ou des reins.
Si vous avez une infection ou si vous ne vous sentez pas bien.
If you have a heart condition, such as if you have had a heart attack in the past or if you have an unusual heartbeat.
Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take idarubicin
Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about idarubicin and will provide a full list of side-effects which you may experience from taking it.
Idarubicin will be given to you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take each day - it is important that you take idarubicin exactly as you are told to. Your dose will also be printed on the label of your pack. If you are unsure about what to do, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
Swallow the capsules whole with a drink of water. Do not open or chew the capsules. Try to take idarubicin at the same time each day, as this will help you to remember to take your doses. You can take the capsules before food, or after a light meal if preferred.
Your doctor will tell you how long your course of treatment will last. For some people this can just be a single dose; for others it can be a three-day course of treatment. You may or may not be asked to repeat the course of treatment after a few weeks.
If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice on what to do. You will be told whether to take the dose again, or wait until the next dose is due.
Tirer le meilleur parti de votre traitement
You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during treatment.
Idarubicin lowers the number of white cells in your blood, increasing the chance of you getting an infection. You should take certain precautions to reduce the risk of infection - if possible, avoid people with infections and let your doctor know if you think you are getting a sore throat or if you have a high temperature.
Idarubicin may colour your urine red. There is no need to be concerned about this as it will go after a day or so. A few people taking idarubicin have noticed that their skin and nails have become discoloured too, although this occurs less often than the colour change to urine.
It is important that you do not get pregnant or father a child while you are taking idarubicin. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. To prevent pregnancy, women should use effective contraception for at least six months after finishing treatment. Men should continue to use contraception for three months after finishing treatment.
While you are taking idarubicin and for a while after you stop treatment, do not have any immunisations (vaccinations) without talking to your doctor first. Idarubicin lowers your body's resistance so there is a chance that you may get an infection from some vaccines.
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.
Poursuivre la lecture ci-dessous
Can idarubicin cause problems?
Along with their useful effects, most medicines can cause side-effects although not everyone experiences them. Before you start treatment with idarubicin, your doctor will discuss with you the possibility of unwanted side-effects occurring. The table below contains some of the most common ones. You will find a full list of side-effects in the manufacturer's information leaflet supplied with your capsules.
Très fréquente idarubicin side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Diarrhée | Buvez beaucoup d'eau pour remplacer les liquides perdus. Si cette situation persiste, consultez votre médecin |
Se sentir malade (nausées) ou être malade (vomissements) | Conservez des aliments simples. Informez votre médecin, car un médicament anti-maladie peut vous aider. |
Sore mouth or mouth ulcers | Se brosser les dents 2 à 3 fois par jour avec une brosse à dents souple et utiliser régulièrement un bain de bouche peut aider à prévenir ce problème. Si les aphtes deviennent un problème, parlez-en à votre médecin. |
A high temperature (fever), or symptoms of an infection | Informez-en immédiatement votre médecin |
Headache, tummy (abdominal) pain, chills, hair loss, lack of appetite, rash | Speak with your doctor or clinic for advice |
Other common side-effects include anaemia, bleeding, heart problems, and reduced numbers of blood cells | Votre médecin vérifiera les éléments suivants |
If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist.
How to store idarubicin
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Return any unused or unwanted capsules to your clinic or pharmacy to destroy. They will need special disposal.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Zavedos® Capsules 5 mg and 10 mgPfizer Limited, The electronic Medicines Compendium. Daté de novembre 2021.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 18 juin 2026
19 Jun 2023 | Dernière version

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