Lacosamide pour l'épilepsie
Vimpat
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 17 oct. 2022
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Lacosamide is prescribed alongside other anti-epilepsy medicines.
Take it twice a day. Try not to miss any doses.
The most common side-effects are feeling dizzy, feeling sick (nausea), headache and blurred vision.
At a glance
Lacosamide is a medicine used to treat focal seizures in epilepsy.
It is prescribed alongside other anti-epilepsy medicines.
Take lacosamide twice a day, every day, exactly as your doctor tells you.
Do not stop taking lacosamide suddenly, as this can cause problems.
Side effects can include dizziness, sleepiness, headache, and nausea.
If you have suicidal thoughts or mood changes, tell your doctor straightaway.
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About lacosamide
Type de médicament | Un médicament anti-épileptique |
Utilisé pour | Epilepsy with focal seizures, in adults and in children aged over 2 years |
Aussi appelé | Vimpat® |
Disponible sous forme de | Comprimés, médicament liquide oral et injection |
Lacosamide is used alongside other medicines in the treatment of focal seizures, which are a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a focal seizure, the burst of electrical activity stays in one part of the brain and therefore you tend to have localised or 'focal' symptoms. Because different parts of the brain control different functions, your symptoms will depend on which part of your brain is affected. Focal seizures can sometimes develop into seizures which affect all of your brain. These are called secondary generalised seizures.
Lacosamide is prescribed for people who have focal seizures, which may or may not be followed by secondary generalised seizures. It is prescribed alongside other anti-epilepsy medicines. It works by stabilising the electrical activity in your brain.
Before taking lacosamide
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lacosamide it is important that your doctor knows:
Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.
If you have a heart rhythm disorder.
Si vous avez des problèmes avec le fonctionnement de votre foie, ou si vous avez des problèmes avec le fonctionnement de vos reins.
Si vous prenez ou utilisez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
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How to take lacosamide
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lacosamide, and will also provide you with a full list of the side-effects which you could experience from taking it.
Take lacosamide exactly as your doctor tells you to. You will be asked to take two doses daily, one dose in the morning and one in the evening. It is likely that you will be prescribed a low dose when you first start taking it, and then your dose will be increased as your body gets used to it. Your doctor or pharmacist will explain this to you, and directions will also be printed on the label of the pack to remind you about what the doctor said to you.
You can take lacosamide either with or without meals. Swallow the tablet with a drink of water.
If you forget to take a dose at your usual time, take it as soon as you remember unless it is within six hours of your next dose, in which case leave out the missed dose. Make sure you take the next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireEssayez de respecter vos rendez-vous réguliers avec votre médecin. Cela permet à votre médecin de suivre vos progrès.
Lorsque vous commencez un nouveau traitement pour l'épilepsie, il peut y avoir un changement dans le nombre ou le type de crises que vous ressentez. Votre médecin vous conseillera à ce sujet.
Lacosamide can make you feel dizzy, especially when you first start treatment. Take care that you do not fall or trip when moving around.
Drinking alcohol while you are on lacosamide can increase feelings of dizziness and may not be recommended for you. Ask for your doctor's advice.
Pendant que vous êtes traité pour l'épilepsie, il existe un petit risque que vous développiez des changements d'humeur, des pensées perturbantes et des sentiments suicidaires. Si cela se produit, vous devez en informer votre médecin immédiatement.
People with epilepsy must stop driving at first. Your doctor will advise you about if and when it may be possible for you to resume driving again.
Many anti-epileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist avant you become pregnant.
You need to take lacosamide regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.
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Can lacosamide cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with lacosamide. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common lacosamide side-effects | Que puis-je faire si je ressens cela ? |
Feeling dizzy, sleepy, tired or unsteady; double vision | Take care that you do not fall or trip when moving around. Do not drive and do not use tools or machines |
Maux de tête | Buvez beaucoup d'eau et demandez à un pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin |
Feeling sick (nausea), constipation, wind | Stick to simple foods - avoid fatty or spicy meals |
Changes in mood, difficulties thinking, poor co-ordination, feeling shaky, unusual eye movements | Si l'un de ces éléments devient problématique, discutez-en avec votre médecin |
Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.
How to store lacosamide
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Once a bottle of Vimpat® Syrup has been opened, it will keep for four weeks. After this time, make sure you have a fresh supply.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide, afin que le médecin sache ce qui a été pris.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous devez subir une opération ou un traitement dentaire, veuillez informer la personne effectuant le traitement des médicaments que vous prenez.
If you buy any medicines, check with a pharmacist that they are safe to take with your prescribed medicines.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is a focal seizure and how does lacosamide help?
A focal seizure is a short episode caused by abnormal electrical activity in one specific part of the brain. The symptoms you experience depend on which part of the brain is affected. Lacosamide works by stabilising this electrical activity in the brain to help manage these seizures.
Can lacosamide be taken on its own for focal seizures?
No, lacosamide is prescribed to be used alongside other anti-epilepsy medicines. It is not intended to be a standalone treatment for focal seizures.
What should I do if I forget to take a dose of lacosamide?
If you miss a dose, take it as soon as you remember. However, if it's within six hours of your next scheduled dose, you should skip the missed dose and just take your next dose at the correct time. Do not take two doses at once to compensate for a forgotten one.
Will I be able to drive while taking lacosamide?
Initially, people being treated for epilepsy must stop driving. Your doctor will provide advice on if and when it might be possible for you to resume driving, as this is a decision made on an individual basis with your doctor.
What should I do if I feel dizzy or unsteady after starting lacosamide?
Dizziness is a common side-effect, especially when you first start treatment. You should be careful to avoid falls or trips when moving around. Also, you should not drive or operate machinery if you are experiencing dizziness, sleepiness, unsteadiness, or double vision.
How long can I use Vimpat® Syrup after opening the bottle?
Once a bottle of Vimpat® Syrup has been opened, it remains effective for four weeks. After this period, you should get a fresh supply.
Is it safe to stop taking lacosamide if my seizures improve?
No, you should not stop taking lacosamide suddenly, even if your seizures seem to be under control. Stopping treatment abruptly can cause problems. If it becomes necessary to stop, your doctor will advise you on how to gradually reduce your dose.
Lectures complémentaires et références
- Manufacturer's PIL, Vimpat® 50 mg, 100 mg, 150 mg and 200 mg film-coated tablets; UCB Pharma Limited, The electronic Medicines Compendium. Dated June 2022.
- Manufacturer's PIL, Vimpat® 10 mg/ml syrup; UCB Pharma Limited, The electronic Medicines Compendium. Dated June 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Next review due: 15 Mar 2027
17 oct. 2022 | Dernière version

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