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Mébévérine

Colofac, Aurobeverine

Mebeverine eases bloating and tummy cramps associated with conditions like irritable bowel syndrome.

If you develop any new symptoms, or if your symptoms worsen, or if your symptoms have not improved within two weeks, you should see your doctor for advice.

Side-effects are rare.

At a glance

  • Mebeverine is an antispasmodic medicine used for bloating and crampy pain in the lower tummy.

  • It works by relaxing muscles in the wall of your intestines.

  • Take mebeverine about 20 minutes before your three main meals.

  • Swallow tablets and capsules whole with water; do not chew them.

  • If symptoms do not improve within two weeks, see your doctor for advice.

  • Rarely, mebeverine can cause an itchy rash or swelling around the face.

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About mebeverine

Type de médicament

An antispasmodic

Utilisé pour

Relief of symptoms caused by gastrointestinal cramps (in adults)

Aussi appelé

Colofac®; Aurobeverine®
Combination brands: Fybogel® Mebeverine sachets (mebeverine with ispaghula husk)

Disponible sous forme de

Tablets, modified-release capsules and oral liquid medicine

Mebeverine is an antispasmodic medicine which is taken to relieve bloating and crampy pain in the lower tummy (abdomen). These symptoms are commonly associated with the gastrointestinal condition called le syndrome du côlon irritable. Mebeverine works on certain muscles in the wall of your intestines, causing them to relax. This eases the pain and cramps.

Mebeverine is available on prescription and you can also buy some packs from a pharmacy, without a prescription.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking mebeverine it is important that your doctor or pharmacist knows:

  • If you are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.

  • If you have severe constipation, or if you feel your bowel is not working properly.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about mebeverine and any side-effects which you may experience from taking it. Take mebeverine exactly as directed on the label.

  • If you have been supplied with 135 mg tablets: the usual dose is one tablet three times daily. Most people find it is best to take the doses about 20 minutes before the three main meals of the day. Swallow the tablets with a small glassful of water. Do not chew the tablets, as they have an unpleasant taste.

  • If you have been supplied with 50 mg in 5 ml liquid medicine: the dose information will be printed on the label of the pack that you have been given. Take the doses about 20 minutes before your three main meals of the day if you can.

  • If you have been supplied with 200 mg capsules (Colofac® MR brand): take one capsule twice daily, one in the morning and one in the evening. Try to take the capsules about 20 minutes before a meal and swallow each dose with a small glassful of water (at least 100 ml). Do not chew or open the capsules, as this would spoil the coating which controls how the mebeverine is released.

  • If you forget to take a dose, do not take two doses together to make up for the missed dose - just continue with the next dose when it is due.

  • It is generally recommended that you take mebeverine only when necessary. So, start taking it when your symptoms flare up, and continue to take it until you feel better. Stop taking it when your symptoms settle down again (this is usually within a week or two).

  • If you develop any new symptoms, or if your symptoms get worse, make an appointment to see your doctor for further advice.

  • If you have bought mebeverine for irritable bowel syndrome and your symptoms have not improved within two weeks of taking it, you should see your doctor for advice (even if you have previously been diagnosed by your doctor).

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Any side-effects from mebeverine are usually mild and rarely cause a problem. You will find a full list in the manufacturer's information leaflet supplied with your medicine.

A few people have developed an allergic-type reaction which has included an itchy rash or swelling around the face. Although these symptoms occur rarely, you should let your doctor know if you develop this type of reaction. Alternatively, go to the accident and emergency department of your local hospital.

If you experience any other symptoms which you think may be due to mebeverine, please speak with your doctor or pharmacist for further advice.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous achetez des médicaments, vérifiez toujours avec un pharmacien qu'ils sont compatibles avec vos autres médicaments.

If you are due to have an operation, tell the person carrying out the treatment which medicines you are taking.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

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Questions fréquemment posées

Can I take mebeverine if I am trying to conceive?

The article states that if you are pregnant or breastfeeding, you should only take medicines on the recommendation of a doctor. It's best to consult your doctor or pharmacist if you are planning a pregnancy to ensure mebeverine is suitable for you.

What should I do if my irritable bowel syndrome symptoms don't improve after two weeks of taking mebeverine?

If you have bought mebeverine for irritable bowel syndrome and your symptoms have not improved within two weeks of taking it, you should see your doctor for advice, even if you have previously been diagnosed by your doctor. This also applies if you develop any new symptoms or if your symptoms get worse.

Is it safe to chew mebeverine tablets or open the capsules if I have trouble swallowing?

No, it is not recommended to chew mebeverine tablets as they have an unpleasant taste. For the 200 mg capsules (Colofac® MR brand), you should not chew or open them because this would spoil the coating that controls how the mebeverine is released. If you have difficulty swallowing, you may want to discuss alternative forms or strategies with your doctor or pharmacist.

How long should I continue taking mebeverine once my symptoms improve?

It is generally recommended that you take mebeverine only when necessary. You should start taking it when your symptoms flare up and continue until you feel better. Once your symptoms settle down again, typically within a week or two, you can stop taking it.

What are the common side-effects of mebeverine?

Side-effects from mebeverine are usually mild and rarely cause a problem. A full list can be found in the manufacturer's information leaflet. A few people have experienced an allergic-type reaction, such as an itchy rash or swelling around the face. If you develop this type of reaction, you should let your doctor know or go to the accident and emergency department of your local hospital. For any other symptoms you think might be due to mebeverine, speak with your doctor or pharmacist.

Can I take mebeverine with my other regular medications?

Before you start taking mebeverine, it's important that your doctor or pharmacist knows about any other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. This allows them to check for any potential interactions.

Lectures complémentaires et références

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 26 oct. 2026
  • 27 oct. 2023 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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