Comprimés de mélatonine pour l'insomnie
Adaflex, Circadin
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 30 août 2023
Respecte les directives éditoriales
- TéléchargerTélécharger
- Partager
- Language
- Discussion
- Version audio
- Add to preferred sources on Google
Melatonin is useful in helping to promote sleep in people over the age of 55 years who have difficulty sleeping. It also helps to promote sleep in children with learning difficulties such as Autism Spectrum Disorder (ASD) and ADHD.
Take one 2 mg tablet 1-2 hours before bedtime, with a snack.
Melatonin will make you feel sleepy, so do not drive and do not use tools or machines until this effect has worn off.
At a glance
Melatonin is a sleeping tablet that helps with poor sleep.
It is prescribed for certain adults and children with specific conditions.
Take melatonin exactly as your doctor tells you, usually 1-2 hours before bedtime.
Do not drink alcohol or take it for longer than your doctor advises.
Common side-effects can include feeling tired, headache, or indigestion.
If you have side-effects that worry you, speak to your doctor or pharmacist.
Dans cet article:
Video picks for Médicaments du système nerveux
Continuez à lire ci-dessous
About melatonin
Type de médicament | Hypnotique (comprimé pour dormir) |
Utilisé pour | Sommeil perturbé |
Aussi appelé | Adaflex®; Ceyesto®; Circadin®; Civasta®; Slenyto®; Syncrodin® |
Disponible sous forme de | Modified-release tablets, tablets, capsules and oral liquid medicine |
Sommeil perturbé can mean that you have difficulty getting to sleep, or that you wake up for long periods during the night, or that you wake early, or that you do not feel refreshed in the mornings.
Insomnia is a fairly common condition, but it does not usually last for long. Melatonin is a hormone which occurs naturally in the body and is associated with the control of the body's sleep pattern. As we grow older the amount of naturally occurring melatonin in the body reduces. Taking melatonin adds to the body's natural supply and helps to promote and improve the quality of sleep.
Circadin® and Civasta® tablets are prescribed for people over the age of 55 years who have insomnia, or difficulty sleeping.
Slenyto® tablets are prescribed for poor sleep in children between the ages of 2 years and 18 years with Autism Spectrum Disorder (ASD) or Smith-Magenis syndrome.
Adaflex® and Ceyesto® tablets are prescribed for poor sleep in children aged 6 to 17 years with ADHD. They can also be prescribed for adults who experience jet lag.
Syncrodin® tablets are prescribed for adults who experience jet lag.
Sometimes a doctor may prescribe melatonin for other groups of people with sleeping problems. If this is the case for you, the way you take melatonin and your dose may be different from the information in this leaflet. Follow your doctor's instructions carefully and ask your doctor or pharmacist if you are unsure of anything.
Before taking melatonin
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking melatonin it is important that your doctor or pharmacist knows:
Si vous avez des problèmes avec le fonctionnement de votre foie, ou avec le fonctionnement de vos reins.
If you have an autoimmune disease - a condition in which the body is attacked by its own overactive immune system. It includes conditions such as polyarthrite rhumatoïde, multiple sclerosis, and lupus.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
Continuez à lire ci-dessous
How to take melatonin
Retour au sommaireBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about melatonin and will provide you with a full list of the side-effects which you may experience from taking it.
Take melatonin exactly as your doctor tells you to. For adults the dose is usually one 2 mg tablet daily, taken 1-2 hours before bedtime. For children with ASD the usual starting dose is 2 mg taken 30 minutes to one hour before bedtime. Your child's doctor may increase the dose slowly to get a better response.
Take the tablet with a snack or after eating some food. This will help the medicine to work later into the night. Swallow the tablet whole - do not break or crush the tablet because it is designed to release melatonin slowly over a few hours.
If you forget to take a tablet at the usual time but you remember before you go to sleep, take it when you remember. If you do not remember until the following day, just take the next dose as usual. Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Retour au sommaireDo not take melatonin for longer than your doctor advises. It can be prescribed for up to 13 weeks for adults over 55.
Do not drink alcohol while you are taking melatonin because it will reduce the medicine's effectiveness in helping you to sleep.
Try to keep your regular appointments with your doctor. This is so your progress can be monitored.
There are some general recommendations that may help promote good sleep. Try to reduce the amount of caffeine you drink, especially in the afternoon and evening. Try to avoid eating heavy meals or drinking alcohol before bedtime. Exercise early in the day, rather than in the evening.
Continuez à lire ci-dessous
Can melatonin cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects but not everyone experiences them. The table below contains some of the side-effects associated with melatonin. Children may be more likely than adults to experience these side-effects. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Melatonin side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je ressens cela ? |
Feeling tired or sleepy | Do not drive and do not use tools or machines until these effects have worn off |
Maux de tête | Buvez beaucoup d'eau et demandez à un pharmacien de vous recommander un antidouleur approprié. Si les maux de tête persistent, informez votre médecin |
Indigestion, feeling sick (nausea), stomach ache | Optez pour des aliments simples - évitez les repas riches ou épicés |
Feeling irritable or restless, mood swings, dry mouth, abnormal dreams, night sweats, dry or itchy skin, pains in the arms or legs | Si l'un de ces éléments devient problématique, parlez-en à votre médecin |
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice. Children with ASD may be more likely to experience mood swings, irritability or aggression when taking melatonin.
How to store melatonin
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous subissez une opération ou un traitement dentaire, informez toujours la personne effectuant le traitement des médicaments que vous prenez.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What is insomnia and how does melatonin help?
Insomnia is a common condition where you have difficulty getting to sleep, wake up for long periods during the night, wake early, or don't feel refreshed in the mornings. Melatonin is a natural hormone in your body that controls your sleep pattern. As you get older, your natural melatonin supply decreases. Taking melatonin supplements adds to your body's supply, which then helps promote and improve the quality of your sleep.
Are there common daily habits that I should avoid or adopt to help melatonin work better?
Yes, there are a few habits that can help. You should avoid drinking alcohol while taking melatonin as it reduces its effectiveness. It's also recommended to reduce caffeine, especially in the afternoon and evening, and avoid heavy meals before bedtime. Exercising earlier in the day rather than in the evening can also be beneficial.
How long can I expect to be on melatonin treatment?
You should not take melatonin for longer than your doctor advises. For adults over 55, it can be prescribed for up to 13 weeks.
When should I take my melatonin tablet if I have forgotten a dose?
If you forget to take your tablet at the usual time but remember before you go to sleep, take it then. If you don't remember until the following day, just take your next dose as usual. Do not take two doses together to make up for a forgotten dose.
What are some common side effects of melatonin and how can I manage them?
Common side-effects, affecting fewer than 1 in 10 people, include feeling tired or sleepy, headache, indigestion, feeling sick, or stomach ache. If you feel tired or sleepy, avoid driving or using tools/machines. For headaches, drink water and consider a painkiller, and if they persist, tell your doctor. For indigestion or feeling sick, stick to simple foods and avoid rich or spicy meals. Children, especially with ASD, might experience mood swings, irritability, or aggression.
Can children take melatonin, and for what conditions?
Yes, children can take melatonin. Slenyto® tablets are prescribed for poor sleep in children aged 2-18 years with Autism Spectrum Disorder (ASD) or Smith-Magenis syndrome. Adaflex® and Ceyesto® tablets are prescribed for poor sleep in children aged 6-17 years with ADHD. The dose and how it's taken may differ, so always follow your doctor's instructions.
I'm having an operation soon. Should I tell my surgeon or dentist about taking melatonin?
Yes, it is important to always tell the person carrying out any operation or dental treatment which medicines you are taking, including melatonin.
Lectures complémentaires et références
- Manufacturer's PIL, Circadin® 2 mg prolonged-release Tablets; Flynn Pharma Ltd, The electronic Medicines Compendium. Dated October 2021.
- Manufacturer's PIL, Slenyto® 1 mg and 5 mg prolonged release tablets; Flynn Pharma Ltd, The electronic Medicines Compendium. Dated October 2021.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
Continuez à lire ci-dessous
About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 29 août 2026
30 août 2023 | Dernière version

Demandez, partagez, connectez-vous.
Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.
Inscrivez-vous à la newsletter Patient
Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.
By subscribing you accept our Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.