Passer au contenu principal

Melphalan tablets

Melphalan will be prescribed for you by a specialist doctor.

Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.

If you think you are getting an infection or if you have a high temperature, please contact your doctor straightaway.

Sélections de vidéos pour Traitement du cancer et médicaments

Continuez à lire ci-dessous

About melphalan tablets

Type de médicament

An alkylating chemotherapy medicine

Utilisé pour

Multiple myeloma; polycythaemia vera

Disponible sous forme de

Comprimés

Melphalan is used to treat some cancers and conditions where cells in the body rapidly divide and multiply. It is most commonly prescribed for conditions such as multiple myeloma et polycythaemia vera. Multiple myeloma is a cancer of the bone marrow. Polycythaemia vera is a bone marrow disease that leads to an abnormal increase in the number of red blood cells in the body. It makes your blood 'thicker' and can make you feel dizzy and short of breath.

In these conditions, certain cells in the body grow and multiply too fast. Melphalan works by preventing cells from multiplying. This reduces the number of cancer cells or unwanted blood cells.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking melphalan it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • Si vous avez des problèmes avec le fonctionnement de vos reins.

  • If you have an infection or feel unwell.

  • If you have a rare inherited blood condition called porphyria.

  • Si vous avez déjà eu une réaction allergique à un médicament.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

Continuez à lire ci-dessous

  • Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of tablets. These will give you more information about melphalan and will provide you with a full list of the side-effects which you may experience from taking it.

  • Melphalan will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how to take it. The dose you are prescribed will depend upon the reason why you are taking it, so it is important that you take the tablets exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you but if you are unsure about how to take the tablets, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.

  • Swallow melphalan tablets whole with a drink of water. Do not break, crush or chew the tablets before you swallow.

  • If you are sick shortly after taking a dose, or if you forget to take a dose at the correct time, contact your doctor or clinic for advice on what to do.

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with melphalan.

  • It is important that you do not get pregnant or father a child while you are taking melphalan. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you would like to have children in the future, you should ask your doctor for advice about family planning before you begin taking melphalan. This is particularly important if you are a man, as there is a risk of reduced male fertility or sterility with melphalan treatment.

  • While you are taking melphalan and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking with your specialist doctor first. Melphalan lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

Continuez à lire ci-dessous

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. While you are taking melphalan you should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment with melphalan, although not everyone experiences these. The table below contains some of the side-effects associated with melphalan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:

Very common melphalan side-effects (these affect more than 1 in 10 people)

Que puis-je faire si je ressens cela ?

A high temperature, or symptoms of an infection

Let your doctor know about this straightaway

Se sentir malade (nausée) ou être malade (vomissements)

Stick to simple foods. Let your doctor know about this, as you can be given an anti-sickness medicine

Diarrhée

Drink plenty of water to replace lost fluids. If this continues, speak with your doctor

Common melphalan side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je ressens cela ?

Ulcères buccaux

Brushing your teeth 2-3 times a day with a soft toothbrush and regularly using a mouth rinse may help to prevent this. If mouth ulcers become a problem, speak with your doctor

Raised levels of urea in your blood

Votre médecin vérifiera cela

Hair loss

This is not permanent but speak with your doctor if you are concerned about it

Si vous ressentez d'autres symptômes que vous pensez être dus aux comprimés, veuillez consulter votre médecin ou votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Melphalan tablets should be stored in a refrigerator at 2°C to 8°C and kept dry.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

symptom checker

Vous n'êtes pas sûr de mélanger des médicaments ?

Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.

Lectures complémentaires et références

Continuez à lire ci-dessous

Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 21 août 2027
  • 17 août 2024 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
flu eligibility checker

Demandez, partagez, connectez-vous.

Parcourez les discussions, posez des questions et partagez vos expériences sur des centaines de sujets de santé.

Inscrivez-vous à la newsletter Patient

Votre dose hebdomadaire de conseils de santé clairs et fiables - rédigés pour vous aider à vous sentir informé, confiant et maître de la situation.

Veuillez entrer une adresse e-mail valide

En vous abonnant, vous acceptez notre Politique de confidentialité. Vous pouvez vous désabonner à tout moment. Nous ne vendons jamais vos données.