Comprimés de misoprostol pour les ulcères d'estomac
Cytotec
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour : 11 mars 2025
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Misoprostol tablets are taken to prevent or treat stomach or duodenal ulcers.
Take the tablets with a meal or snack.
The most common side-effect is diarrhoea. If this happens, drink plenty of water.
Dans cet article :
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About misoprostol
Type de médicament | A prostaglandin analogue anti-ulcer medicine |
Utilisé pour | To help prevent stomach and duodenal ulcers; to treat an existing stomach or duodenal ulcer |
Également appelé | Cytotec®; |
Disponible en | Tablettes |
Misoprostol is similar to naturally made protective substances in your body, called prostaglandins. Prostaglandins help to protect the lining of your stomach and intestines. Taking misoprostol will help prevent you from getting ulcers in your stomach and the part of your intestines next to your stomach, which is called the duodenum.
Ulcers in these areas are often caused by taking painkillers known as non-steroidal anti-inflammatory drugs (or NSAIDs for short). Two common examples of these medicines are diclofenac and naproxen - medicines often taken by people with arthritis. NSAIDs can reduce the natural amount of prostaglandins in your stomach and intestines, which causes indigestion and can lead to ulcers forming. Misoprostol tablets will replace your natural prostaglandins so that you can continue getting benefit from your NSAID painkiller. If you already have an ulcer, misoprostol will help it to heal.
Misoprostol is also available in combination with the NSAID diclofenac. Combination brands of tablet are sometimes prescribed for people with arthritis. Taking a combination tablet can help to reduce the total number of tablets that you need to take each day.
Occasionally, misoprostol may be prescribed for a use which is not covered by this leaflet. If you have been prescribed misoprostol for a reason other than those listed above, you should ask your doctor if you have any questions about your treatment.
Before taking misoprostol
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking misoprostol it is important that your doctor knows:
Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.
If you have been told that you have an inflammatory bowel disease, such as ulcerative colitis or Crohn's disease.
If you have any of the following: heart disease, low or high blood pressure, blood vessel disease.
Si vous prenez ou utilisez d'autres médicaments. Cela comprend tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
Poursuivre la lecture ci-dessous
How to take misoprostol
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about misoprostol, and will also provide you with a full list of side-effects which you could experience from taking it.
Take the tablets exactly as your doctor tells you to. You will be asked to take one tablet either two, three or four times a day. Your doctor or pharmacist will tell you which of these doses is right for you, and this information will also be printed on the label of the pack of tablets to remind you about what was said to you. Each time you take a dose, take the tablet just after eating a meal or with a snack.
If you forget to take a dose, take it as soon as you remember (with a snack). However, if when you remember it is nearly time for your next dose then leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Tirer le meilleur parti de votre traitement
Essayez de vous rendre à vos rendez-vous réguliers avec votre médecin. Il pourra ainsi vérifier vos progrès.
If you are taking misoprostol because you already have an ulcer then you will be prescribed a course of treatment lasting 4-8 weeks. If you are taking misoprostol to prevent you from getting an ulcer then your treatment is likely to be long-term, especially if you are taking anti-inflammatory medicines regularly. Continue to take misoprostol until your doctor advises you otherwise.
If you need to take an indigestion remedy, you should choose one that does not contain magnesium. This is because magnesium can increase the risk of diarrhoea as a side-effect. Your pharmacist will be able to give you advice about which antacids and other medicines are suitable for you to buy to take alongside misoprostol.
It is very important that you do not become pregnant while on misoprostol. This is because misoprostol is harmful to unborn babies. If you have not yet been through the menopause and this is something which could be a concern for you, make sure you ask your doctor about what contraception is suitable for you and your partner before you start taking misoprostol.
Poursuivre la lecture ci-dessous
Can misoprostol cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with misoprostol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Very common misoprostol side-effects (these affect more than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Diarrhée | Make sure you take misoprostol tablets after food to minimise this. Drink plenty of water to replace lost fluids. If it continues or becomes severe, speak with your doctor for further advice |
Éruption | En cas de troubles, demandez conseil à votre médecin. |
Common misoprostol side-effects (these affect fewer than 1 in 10 people) | Que puis-je faire si je suis confronté à cette situation ? |
Feeling sick (nausea) or being sick (vomiting), tummy (abdominal) pain, indigestion, wind | Make sure you take misoprostol tablets after food. Avoid rich and spicy meals |
Saignement vaginal | Parlez-en à votre médecin |
Sensation de vertige | Dans ce cas, ne conduisez pas et n'utilisez pas d'outils ou de machines pendant la durée de l'affection. |
Headache, constipation | If either of these becomes troublesome, drink plenty of water and ask your pharmacist to recommend a suitable remedy |
Si vous ressentez d'autres symptômes qui pourraient être dus aux comprimés, demandez conseil à votre médecin ou à votre pharmacien.
How to store misoprostol
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous devez subir une opération ou un traitement dentaire, indiquez à la personne chargée du traitement les médicaments que vous prenez.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Cytotec® 200 microgram tabletsPfizer Limited, The electronic Medicines Compendium. Daté d'octobre 2020.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 10 mars 2028
11 Mar 2025 | Dernière version

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