Comprimés de modafinil
Provigil
Révision par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour le 14 août 2023
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Take modafinil at the same times each day to avoid missing any doses.
The most common side-effects include headache, feeling sick (nausea) and feeling dizzy.
You should not become pregnant whilst taking modafinil. Ask your doctor about which contraceptive methods are suitable for you while you are taking modafinil - hormonal contraceptives are not suitable.
Dans cet article :
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About modafinil
Type de médicament | A central nervous system stimulant |
Utilisé pour | Daytime sleepiness associated with narcolepsy in adults |
Également appelé | Provigil® |
Disponible en | Tablettes |
Narcolepsy is a long-term problem that affects your sleep. You feel excessively tired during the daytime but have disturbed night-time sleep. You can also have sleep attacks where you fall asleep at inappropriate times during the day without any warning.
Although there is no cure for narcolepsy, modafinil can help to control your symptoms. Modafinil works by stimulating the central nervous system to increase your alertness and reduce excessive sleepiness during the day.
Before taking modafinil
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking modafinil it is important that your doctor knows:
Si vous êtes enceinte, si vous essayez d'avoir un enfant ou si vous allaitez.
Si vous avez des problèmes de fonctionnement du foie ou des reins.
If you have a heart condition or high blood pressure (hypertension).
If you have ever had a mental health problem such as depression, psychosis or mania.
Si vous avez déjà eu un problème de toxicomanie ou d'alcoolisme.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.
Si vous avez déjà eu une réaction allergique à un médicament.
Clinical author's note Michael Stewart 01/03/2020: Based on post-marketing reports from the USA, modafinil (Provigil®) may harm an unborn child. Modafinil should not be used during pregnancy. Women of childbearing potential must use effective contraception during treatment with modafinil and for two months after stopping. Discuss with your doctor which forms of contraception are suitable for you, as hormonal contraceptives are made less effective by modafinil. Alternative treatment options for narcolepsy should be used during pregnancy, such as behaviour modifications, good sleeping habits and scheduled daytime naps.
Poursuivre la lecture ci-dessous
How to take modafinil
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about modafinil and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. There are two strengths of tablet available - 100 mg and 200 mg. When you first start modafinil it is usual to be prescribed a dose of 200 mg daily. You may be asked to take this as a single dose of 200 mg in the morning, or divided into 100 mg in the morning and 100 mg at midday. Your doctor or pharmacist will tell you which is right for you. Your dose may be increased after a little while, depending upon your symptoms.
Take your doses with a drink of water to help you swallow the tablet. Do not break or crush the tablet - it should be swallowed whole. You can take modafinil before or after food.
If you forget to take a dose, miss out the forgotten dose completely but make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
Keep your regular appointments with your doctor so that your progress can be monitored. You may need to have your blood pressure and heart rate checked regularly.
Modafinil can cause blurred vision or dizziness in some people and therefore it may affect your ability to use tools or machines, so take care when using them. Sleepiness associated with your condition can add to this.
Taking modafinil is not a replacement for a good sleep routine. It is still important that you aim to get around eight hours of sleep at night if possible. You should try to go to sleep and get up at about the same time each day.
In the UK, you are required by law to let the Driver and Vehicle Licensing Authority (DVLA) know if you are diagnosed with narcolepsy. You may be allowed to drive again when your symptoms are well controlled with medication, but you will need to have regular reviews. Your doctor will advise you about this.
Modafinil should not be used during pregnancy. Women of childbearing potential must use effective contraception during treatment with modafinil and for two months after stopping.
Hormonal contraceptives, including oral contraceptive pills, implants, intrauterine contraceptive devices (IUCDs) and contraceptive patches, are less effective when used with modafinil and are therefore not recommended. Speak to your doctor about which contraceptive methods are suitable for you while you are taking modafinil.
If you are planning to become pregnant you should stop taking modafinil and try alternative treatment options such as good sleep habits and scheduled daytime naps.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking modafinil.
Poursuivre la lecture ci-dessous
Can modafinil cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with modafinil. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Communs modafinil side-effects | Que puis-je faire si je suis confronté à cette situation ? |
Maux de tête | This usually passes within a day or so, but in the meantime, ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor |
Bouche sèche | Essayez de mâcher du chewing-gum sans sucre ou de sucer des bonbons sans sucre. |
Feeling sick (nausea), indigestion, stomach ache | S'en tenir à des repas simples - éviter les aliments riches ou épicés |
Diarrhée | Boire beaucoup d'eau pour remplacer les liquides perdus |
Constipation | Essayez d'avoir une alimentation équilibrée et buvez plusieurs verres d'eau par jour. |
Sensation de vertige ou de fatigue, vision trouble | Take special care when using tools or machines |
Flushing, loss of appetite, nervousness, difficulty sleeping, anxiety, depression, confusion or confused thinking, chest pain, fast heartbeat, numbness or tingling feelings | Speak with your doctor if any of these continue or become troublesome |
Important: if you experience any of the following symptoms, stop taking modafinil and contact your doctor for advice straightaway:
A rash or blisters on the skin.
Any changes to your mood, behaviour, or thinking.
Any suicidal thoughts, or thoughts about harming yourself.
Si vous ressentez d'autres symptômes qui pourraient être dus aux comprimés, demandez conseil à votre médecin ou à votre pharmacien.
How to store modafinil
Conservez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous immédiatement au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez auprès d'un pharmacien qu'ils peuvent être pris avec vos autres médicaments.
Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.
Si vous avez des questions sur ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.
Autres lectures et références
- Manufacturer's PIL, Modafinil (Provigil®) 100 mg and 200 mg tablets; Teva Pharma B.V., The electronic Medicines Compendium. Dated October 2021.
- Médicaments Complet BNF 89ème éditionBritish Medical Association et Royal Pharmaceutical Society of Great Britain, Londres.
Historique de l'article
Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.
Prochaine révision prévue : 13 août 2026
14 Aug 2023 | Dernière version

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