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Phénobarbital pour l'épilepsie

You need to take phenobarbital regularly every day. Take your dose at bedtime.

Phenobarbital may cause you to feel drowsy and unsteady. This often settles down as your body adjusts to the new medicine.

Do not drink alcohol.

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About phenobarbital

Type de médicament

Un médicament anti-épileptique

Utilisé pour

Épilepsie

Disponible sous forme de

Comprimés, liquide oral et injection

Si vous avez épilepsie, it means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable anti-epileptic medication.

Phenobarbital works by stabilising the electrical activity of your brain, which helps to prevent the seizures from occurring.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking phenobarbital it is important that your doctor knows:

  • Si vous êtes enceinte, essayez d'avoir un bébé ou allaitez.

  • Si vous avez des problèmes respiratoires.

  • If you have ever had problems with drug or alcohol dependence.

  • If you have any problems with the way your kidneys work, or with the way your liver works.

  • Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about phenobarbital and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take phenobarbital exactly as your doctor tells you to. It is usual to take one dose a day, at bedtime. Your doctor will tell you how many tablets to take for the dose. This information will also be printed on the label of the pack to remind you about what the doctor said to you. You need to take phenobarbital regularly every day to prevent the fits (seizures) from occurring.

  • Try to take your doses of phenobarbital at the same time each evening. Having a routine like this will help you to remember to take your doses regularly. Swallow the phenobarbital tablets with a drink of water. You can take them either with or without food.

  • If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.

  • When you first start a new treatment for epilepsy there may be a change in the number or type of fits (seizures) you experience. Your doctor will advise you about this.

  • Phenobarbital made by different manufacturers can act in a slightly different way in your body. Because of this, it is recommended that you continue to take tablets/medicine from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same. If you are unsure, or if have any questions about your prescription, please ask your pharmacist to check it for you.

  • Pendant que vous êtes traité pour l'épilepsie, il existe un petit risque que vous développiez des changements d'humeur, des pensées perturbantes et des sentiments suicidaires. Si cela se produit, vous devez en informer votre médecin immédiatement.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to resume driving again. This will usually be after a year free of seizures.

  • Do not stop taking this medicine unless your doctor tells you to do so. Stopping it suddenly can cause your seizures to return and your doctor will want you to reduce your dose gradually if this becomes necessary. Also, taking phenobarbital over a time can lead to your body becoming dependent on it and this is another reason why your doctor will want to reduce your dose slowly.

  • You are advised not to drink alcohol while you are taking phenobarbital. Phenobarbital will make you feel sleepy and drinking alcohol will increase this. Some liquid medicines may contain noticeable amounts of alcohol, read the manufacturer's leaflet for more information.

  • If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking phenobarbital.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside phenobarbital.

  • You should avoid becoming pregnant while you are taking phenobarbital because it could cause harm to your unborn baby.

  • If you are a woman using hormonal contraception ('the pill' or the 'mini pill'), discuss this with your doctor, as phenobarbital interferes with these and could mean you are more likely to become pregnant. Other methods of contraception will be more suitable for you.

  • If you want to have a family, make sure you discuss this with your doctor well in advance of becoming pregnant. This is so that you can be given advice from a specialist before you become pregnant. If you become pregnant while you are taking phenobarbital, you should tell your doctor straightaway.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with phenobarbital. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common phenobarbital side-effects

Que puis-je faire si je ressens cela ?

Feeling unsteady

Getting up or moving more slowly should help. If this continues, let your doctor know

Se sentir somnolent ou fatigué

Make sure your reactions are normal before you use tools or machines

Feeling short of breath, behavioural changes, mood changes (such as feeling irritable, confused, excited or depressed), impaired memory

Si l'un de ces éléments devient problématique, parlez-en à votre médecin

Important: your doctor will have discussed with you the possibility of some less common but more serious side-effects. Let your doctor know straightaway if you experience any of the following:

  • A high temperature (fever) and swollen glands.

  • Une éruption cutanée sévère.

  • Yellowing of your skin or the whites of your eyes (jaundice).

Si vous ressentez d'autres symptômes que vous pensez être dus au médicament, parlez-en à votre médecin ou à votre pharmacien pour obtenir des conseils supplémentaires.

  • Gardez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

  • Liquid medicines should be used within 28 days of opening, unless otherwise stated on the bottle.

Informations importantes sur tous les médicaments

Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.

Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le site web Yellow Card.

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Lectures complémentaires et références

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Historique de l'article

Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.

  • Prochaine révision prévue : 5 mai 2028
  • 5 mai 2025 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Revu par

    Sid Dajani
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