Pivmecillinam for infection
Selexid
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSLast updated 27 janv. 2023
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Make sure you tell your doctor if you are allergic to penicillin. Pivmecillinam is a type of penicillin - do pas take it if you are allergic to penicillin.
Take pivmecillinam tablets with, or straight after, a meal. Make sure you have plenty of water to drink as you take the tablets, and sit or stand upright as you swallow.
Space your doses out evenly over the day and complete the full course of the antibiotic, even if you feel your infection has cleared up.
Si vous avez une réaction allergique (comme un gonflement autour de la bouche, des difficultés à respirer ou une éruption cutanée rouge), contactez immédiatement un médecin.
At a glance
Pivmecillinam is an antibiotic used to treat bacterial infections, including some urinary tract and salmonella infections.
Take tablets with food or a snack, swallow whole, and drink plenty of water while sitting or standing upright.
Complete the full course of antibiotics, even if you feel better, unless your doctor tells you to stop.
Common side effects include feeling sick, vomiting, indigestion, tummy pain, and diarrhoea.
Seek immediate medical help if you develop an itchy rash, swollen face or mouth, or difficulty breathing.
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About pivmecillinam
Type de médicament | Antibiotique à la pénicilline |
Utilisé pour | Infections |
Aussi appelé | Amdinocillin pivoxil (in US); Selexid® |
Disponible sous forme de | Comprimés |
Pivmecillinam is used to treat bacterial infections, such as some urinary tract infections. It is also used to treat infections caused by a type of germ (bacterium) called salmonella. Pivmecillinam works by killing the bacteria causing the infection.
Before taking pivmecillinam
Retour au sommaireSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking pivmecillinam it is important that your doctor or pharmacist knows:
If you have an allergic condition, or if you have ever had an allergic reaction to a medicine. This is particularly important if you have ever had a bad reaction to a penicillin antibiotic.
Si vous êtes enceinte ou si vous allaitez.
If you have any difficulties swallowing.
If you think you may have a blockage in your digestive system.
Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.
If you have a condition that reduces the amount of a substance called carnitine in your body.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
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How to take pivmecillinam
Retour au sommaireBefore you start this antibiotic, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about pivmecillinam and a full list of side-effects which you may experience from taking it.
Take pivmecillinam exactly as your doctor tells you to. You may be asked to take one or two tablets, three or four times daily, depending upon the type of infection you have. Your doctor will tell you which dose is right for you, and this will also be printed on the label of the pack to remind you. Space the doses out evenly during the day.
You should take pivmecillinam with a meal or snack. Swallow the tablets whole - do not chew or crush the tablets. Have plenty to drink as you take the tablets (at least half a glassful), and make sure you are sitting or standing upright so that the tablets don't become stuck in your throat and cause irritation and/or ulcers.
Si vous oubliez de prendre une dose, prenez-en une dès que vous vous en souvenez. Essayez de prendre le bon nombre de doses chaque jour, mais ne prenez pas deux doses en même temps pour compenser une dose oubliée.
Tirer le meilleur parti de votre traitement
Retour au sommaireEven if you feel your infection has cleared up, keep taking this antibiotic until the course is finished (unless you are told to stop by your doctor). This is to prevent the infection from coming back. A course of treatment with this antibiotic usually lasts for a few days. If you still feel unwell after finishing the course, go back to see your doctor.
If you have an infection that keeps coming back or is long-term (chronic), you may be prescribed pivmecillinam to take over a longer period of time. If so, your doctor will ask to see you on a regular basis so that your progress can be monitored. You will need to have a blood test from time to time to check that your kidneys and liver are working properly.
Some people develop thrush (a fungal infection causing redness and itchiness in the mouth or vagina) after taking a course of antibiotics. If this happens to you, speak with your doctor or pharmacist for advice.
If you are using combined oral hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are pas nécessaire during a course of this antibiotic unless you are sick (vomit) or have diarrhoea. If you need further advice about this, speak with your doctor or pharmacist.
Cet antibiotique peut empêcher le vaccin oral contre la typhoïde de fonctionner. Si vous recevez des vaccinations, assurez-vous que la personne qui vous traite sait que vous prenez ce médicament.
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Can pivmecillinam cause problems?
Retour au sommaireAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with pivmecillinam. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common pivmecillinam side-effects - these affect fewer than 1 in 10 people who take this medicine | Que puis-je faire si je ressens cela ? |
Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) pain | Optez pour des aliments simples - évitez les repas riches ou épicés |
Diarrhée | Drink plenty of water to replace any lost fluids. If the diarrhoea becomes severe, or contains blood, let your doctor know immédiatement |
Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these may be signs that you are allergic to a penicillin antibiotic. Do not take any more tablets, and speak with your doctor or go to your local accident and emergency department straightaway.
Si vous ressentez d'autres symptômes que vous pensez être dus à ce médicament, parlez-en à votre médecin ou à votre pharmacien.
How to store pivmecillinam
Retour au sommaireGardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Retour au sommaireInformations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous immédiatement au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Yellow Card website.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
What types of infections can pivmecillinam treat?
Pivmecillinam is used to treat bacterial infections, specifically some urinary tract infections and infections caused by bacteria called salmonella. It works by killing these bacteria.
What should I do if I am pregnant or breastfeeding and need to take pivmecillinam?
If you are pregnant or breastfeeding, it's important to let your doctor or pharmacist know before you start taking pivmecillinam. They will be able to advise you on the best course of action.
Are there specific instructions for taking pivmecillinam tablets to avoid irritation?
Yes, you should swallow the tablets whole without chewing or crushing them. It's also important to drink plenty of fluid (at least half a glassful) with the tablets and remain sitting or standing upright. This helps prevent the tablets from getting stuck in your throat and causing irritation or ulcers.
I'm taking the contraceptive pill. Do I need extra protection while on pivmecillinam?
If you are using combined oral hormonal contraception (the 'pill'), you do not typically need additional contraceptive precautions like condoms when taking this antibiotic, unless you experience vomiting or diarrhoea. If you have any concerns, speak to your doctor or pharmacist for further advice.
Can pivmecillinam affect other medications or treatments?
Yes, pivmecillinam can interact with other medicines. It's important to tell your doctor or pharmacist about all medicines you are taking, including over-the-counter, herbal, and complementary medicines. Also, this antibiotic may stop the oral typhoid vaccine from working, so you should inform anyone treating you for vaccinations that you are taking pivmecillinam.
What are the common side-effects of pivmecillinam and what can I do about them?
Common side-effects include feeling sick (nausea), being sick (vomiting), indigestion, and tummy (abdominal) pain. For these, try to eat simple foods and avoid rich or spicy meals. If you experience diarrhoea, drink plenty of water to replace lost fluids. If diarrhoea becomes severe or contains blood, contact your doctor immediately.
Lectures complémentaires et références
- Manufacturer's PIL, Selexid® 200 mg Film-coated Tablets; Karo Pharma AB, The electronic Medicines Compendium. Dated September 2022.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Prochaine révision prévue : 26 juil. 2027
27 janv. 2023 | Dernière version

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