Ranitidine pour réduire l'acidité gastrique
Zantac
Revu par Sid DajaniDernière mise à jour par Michael Stewart, MRPharmSDernière mise à jour 17 May 2024
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Note de l'auteur clinique Michael Stewart 18/5/2024: Further to earlier notes, all ranitidine products have now been discontinued in the UK. At the time of review there are no branded or generic products containing ranitidine available in the UK. Ranitidine may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Note de l'auteur clinique Michael Stewart 22/02/23: As a precautionary measure all ranitidine-containing products have been discontinued globally whilst the scientific investigation into its risks and benefits is ongoing. It is not known whether ranitidine products will be made available again in the future. If you have any concerns regarding your use of ranitidine please speak to your doctor or a pharmacist.
Note de l'auteur clinique Michael Stewart 21/11/2019: Since October 2019 a large number of ranitidine products have been recalled by their manufacturers. Pharmacies and other retailers have been told to remove these products from sale. The recalls are due to a risk of contamination with a potentially harmful chemical. There may be an ongoing shortage of ranitidine products as a consequence. If you have any concerns about the medicine you are taking you should speak with your pharmacist for advice.
Ranitidine reduces the amount of acid produced by your stomach.
Any side-effects are usually mild and do not last long.
En un coup d'œil
Ranitidine is a medicine that reduces stomach acid, used for conditions like ulcers and acid reflux.
It comes as tablets or a liquid, and some lower strengths can be bought without a prescription.
Take ranitidine as directed, either before or after meals.
Possible side-effects include tummy pain, feeling sick, dizziness, and headache.
Speak to a doctor or pharmacist before taking ranitidine if you have certain symptoms or other medical conditions.
About ranitidine
Type de médicament | médicament antagoniste des récepteurs H2-receptor antagonist |
Utilisé pour | Treatment of conditions caused by too much acid being produced in the stomach |
Aussi appelé | Zantac® (discontinued) |
Disponible sous forme de | Comprimés et médicaments liquides oraux |
Ranitidine belongs to a group of medicines that reduce the amount of acid produced by the cells in the lining of the stomach. They are called 'histamine H2-receptor antagonists', but are commonly also called Bloqueurs H2.
Ranitidine is helpful in the treatment of conditions caused by too much acid being produced in the stomach. These conditions include stomach ulcers (gastric ulcers), ulcers of the upper part of the intestine (duodenal ulcers), acid reflux or heartburn (reflux oesophagitis), and l'indigestion. Ranitidine is also prescribed to treat ulceration of the stomach which has been caused by anti-inflammatoires non stéroïdiens (AINS).
Acid is produced naturally in your stomach to help you digest food. Excessive amounts of acid can irritate the lining of your stomach, causing inflammation, ulcers and other conditions. Ranitidine works by reducing the amount of acid produced by your stomach. This helps to relieve symptoms and assist the healing process where damage has already occurred.
Ranitidine is available on prescription. You can also buy short courses of ranitidine at retail outlets for symptoms such as heartburn, indigestion and hyperacidity in adults and in children over 16 years of age.
Before taking ranitidine
To make sure that this is the right treatment for you, before you start taking ranitidine it is important that you speak with a doctor or pharmacist:
Si vous êtes enceinte ou si vous allaitez.
If you have any of the following symptoms: difficulty swallowing, loss of blood, or weight loss, or if you are being sick.
Si vous avez des problèmes avec le fonctionnement de vos reins.
Si vous avez un trouble sanguin héréditaire rare appelé porphyrie.
Si vous avez déjà eu une réaction allergique à un médicament.
Si vous prenez d'autres médicaments. Cela inclut tous les médicaments que vous prenez et qui sont disponibles à l'achat sans ordonnance, ainsi que les médicaments à base de plantes et les médecines complémentaires.
How to take ranitidine
Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ranitidine and will provide you with a full list of the side-effects which you may experience from taking it.
Take ranitidine exactly as your doctor tells you to, or as directed on the label if you have bought it. There are three different strengths of tablet available - 75 mg, 150 mg and 300 mg. Only the lower strength of tablet can be purchased. Ranitidine is taken once or twice a day.
You can take ranitidine either before or after meals.
If you forget to take a dose at your usual time, you can take it when you remember. However, if it is nearly time to take your next dose when you remember, leave out the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Tirer le meilleur parti de votre traitement
A course of treatment can vary in length depending upon the reason why you are taking ranitidine. It may be just for a few days to relieve your symptoms, or for several weeks to help an ulcer heal. Keep any appointments that you have booked with your doctor so that your progress can be checked.
Some people say that certain foods make their symptoms worse. Foods and drinks that have been suspected of this include peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcoholic drinks. If it seems that a food is aggravating your symptoms, try avoiding it for a while to see if your symptoms improve. Also, try avoiding eating large meals, as these can make your symptoms worse too.
If you are overweight, this puts extra pressure on your stomach and encourages the symptoms of acid reflux. Losing some weight and eating a healthy balanced diet may help you.
Smoking increases the amount of acid produced by the stomach and may make your symptoms worse. If you are a smoker, speak with your doctor or pharmacist about how to quit.
Can ranitidine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with ranitidine, although these are generally mild and do not last long. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Ranitidine side-effects | Que puis-je faire si je ressens cela ? |
Constipation or diarrhoea, tummy pain | Cela devrait bientôt passer |
Sensation de malaise (nausée) | Optez pour des repas simples - évitez les aliments riches ou épicés |
Feeling dizzy, headache | Cela devrait bientôt passer |
If you experience any other symptoms which you think may be due to ranitidine, speak with your doctor or pharmacist for further advice.
How to store ranitidine
Gardez tous les médicaments hors de la portée et de la vue des enfants.
Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.
Informations importantes sur tous les médicaments
Informations importantes sur tous les médicaments
Ne prenez jamais plus que la dose prescrite. Si vous soupçonnez que vous ou quelqu'un d'autre avez pris une surdose de ce médicament, rendez-vous au service des urgences de votre hôpital local. Emportez le contenant avec vous, même s'il est vide.
Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.
Si vous achetez des médicaments, vérifiez toujours avec un pharmacien qu'ils sont sûrs à prendre avec vos autres médicaments.
Si vous subissez une opération ou un traitement dentaire, informez la personne qui effectue le traitement des médicaments que vous prenez.
Ne gardez pas de médicaments périmés ou indésirables. Apportez-les à votre pharmacie locale qui s'en débarrassera pour vous.
Si vous avez des questions concernant ce médicament, demandez à votre pharmacien.
Signaler les effets secondaires d'un médicament ou d'un vaccin
Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne via le Site web de Yellow Card.

Vous n'êtes pas sûr de mélanger des médicaments ?
Vérifiez les interactions possibles entre les médicaments, les compléments et les aliments avant de les prendre ensemble.
Questions fréquemment posées
Can ranitidine be used by children?
Ranitidine can be bought over-the-counter for use in adults and in children over 16 years of age for symptoms like heartburn, indigestion, and hyperacidity.
What happens if I take too much ranitidine?
If you suspect that you or someone else might have taken an overdose of ranitidine, you should go to the accident and emergency department of your local hospital immediately. Remember to bring the medicine container with you, even if it is empty.
How long does a course of ranitidine treatment typically last?
The duration of treatment with ranitidine can vary. It might be for just a few days to relieve symptoms, or it could extend for several weeks, for example, to allow an ulcer to heal fully. It's important to keep any scheduled appointments with your doctor to monitor your progress.
What lifestyle changes can help improve symptoms while taking ranitidine?
Certain foods like peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcohol may worsen symptoms, so avoiding them might help. Eating smaller meals can also be beneficial. If you are overweight, losing weight can reduce pressure on your stomach and improve acid reflux symptoms. Quitting smoking is also recommended, as it increases stomach acid production.
When was Zantac discontinued?
The article states that Zantac® (which is ranitidine) has been discontinued as a brand.
Lectures complémentaires et références
- Manufacturer's PIL, Gavilast® Heartburn and Indigestion 75 mg Film-coated Tablets; Reckitt Benckiser Healthcare (UK) Ltd, The electronic Medicines Compendium. Dated October 2016.
- Médicaments Complets BNF 89e Édition; Association Médicale Britannique et Société Royale Pharmaceutique de Grande-Bretagne, Londres.
À propos de l'auteurVoir la biographie complète

Michael Stewart, MRPharmS
Responsable de l'examen des notices de médicaments – Contractuel, Pharmacien
BPharm (Hons), MRPharmS
Michael est un pharmacien communautaire exerçant dans les Midlands et le South Yorkshire avec plus de 20 ans d'expérience dans le conseil sur les médicaments et les conditions médicales. Il possède une solide expérience en formation dans le domaine de la santé, ayant produit et dispensé des cours de formation pour les équipes de pharmacie et le personnel des établissements de soins résidentiels, y compris les infirmières. Il a également contribué aux comités consultatifs de pharmacie pour la gestion des affections de faible gravité dans la communauté.
À propos du critique

Sid Dajani
Sultan Dajani a obtenu son diplôme à la London School of Pharmacy en 1994 et est devenu le plus jeune membre élu du conseil de la Royal Pharmaceutical Society depuis sa fondation en 1842.
Historique de l'article
Les informations sur cette page sont rédigées et examinées par des cliniciens qualifiés.
Article également disponible en Anglais, Allemand, Espagnol, Français, Italien, Portugais, Hindi, Hébreu, Arabe, and Suédois.
Prochaine révision prévue : 26 avr. 2027
17 May 2024 | Dernière version

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