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Triamterene - un comprimé d'eau ou diurétique

Dyrenium

Clinical author's note Michael Stewart 15/06/2022: Triamterene capsules were discontinued in the UK in November 2021. Currently triamterene is only available in the UK in combination with another diuretic medicine called chlortalidone. At the time of review there are no branded or generic products solely containing triamterene available in the UK. Products may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Triamterene is a 'water' tablet (diuretic) - it will make you want to go to the toilet more often to pass urine.

It may cause your urine to look slightly blue in some lights - this is harmless.

Les effets secondaires éventuels sont généralement légers.


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About triamterene

Type de médicament

A potassium-sparing diuretic

Utilisé pour

Water retention (oedema)

Également appelé

Dyrenium® (USA);
Combinations: Triamterene with chlortalidone, triamterene with hydrochlorothiazide

Disponible en

Triamterene 50 mg/ chlortalidone 50 mg tablets

Triamterene belongs to the group of medicines known as potassium-sparing diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water' tablets. Triamterene is called a potassium-sparing diuretic because, unlike some other diuretics, it does not cause your body to lose potassium. It is used to treat water retention (oedema), and it is also given alongside other diuretics to reduce the amount of potassium they cause your body to lose.

Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless and your legs feel puffy. It is commonly caused by heart failure or liver disease. Triamterene prevents the build-up of this fluid by increasing the amount of urine your kidneys produce.

In the UK, triamterene is only available in combination with another diuretic medicine called chlortalidone. This combination can help cut down on the number of tablets you need to take each day.

Before taking triamterene

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking triamterene it is important that your doctor knows:

  • Si vous êtes enceinte ou si vous allaitez.

  • If you have problems with the way your kidneys work, or any difficulty passing urine.

  • Si vous avez des problèmes de fonctionnement du foie.

  • Si vous êtes diabétique.

  • If you have attacks of gout.

  • If you have been told by a doctor that you have high levels of potassium in your blood.

  • Si vous avez un problème avec vos glandes surrénales, appelé maladie d'Addison.

  • Si vous prenez d'autres médicaments. Cela inclut tous les médicaments disponibles sans ordonnance, ainsi que les médicaments à base de plantes et les médicaments complémentaires.

  • Si vous avez déjà eu une réaction allergique à un médicament.

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How to take triamterene

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about triamterene and will also provide you with a full list of side-effects which you could experience from taking it.

  • Take triamterene exactly as your doctor tells you to. It is usual, to begin with, to take 3-5 capsules a day divided into two doses, one dose with your breakfast and the other at lunchtime. After the first week or so, your doctor is likely to ask you to take the capsules on alternate days only. The directions for taking your doses will be printed on the label of the pack to remind you about what the doctor said to you.

  • Diuretics are best taken no later than mid-afternoon. This is because you will find you may need to go to the toilet a couple of times after taking it and this will disturb your sleep if you take it too late in the day.

  • Swallow the capsules with a drink of water. You can take triamterene either with or without food.

  • If you forget to take a dose of triamterene, take it when you remember if it is only a few hours late. If it is after mid-afternoon, leave out the forgotten dose completely and take your next dose when it is due. Do not take two doses at the same time to make up for a missed dose.

Tirer le meilleur parti de votre traitement

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The balance of salts in your blood may be upset by triamterene so your doctor may want you to have a blood test from time to time to check for this.

  • Diuretics help you to lose water, so you can breathe and move more easily. If, however, you lose too much fluid, you may become lacking in fluid in the body (dehydrated). This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted.

  • Because triamterene is a potassium-sparing diuretic, you should try to avoid things with a high potassium content, such as 'salt substitutes'. This is so the level of potassium in your body does not become too high.

  • Treatment with diuretics is usually long-term, so continue to take triamterene unless your doctor advises you otherwise.

  • If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take alongside your prescribed medicines.

  • Triamterene can cause your urine to look slightly blue in some lights - this is harmless and nothing to be concerned about.

Si vous prenez également de l'hydrochlorothiazide en association avec ce médicament

  • Des études ont suggéré que la prise de doses élevées d'hydrochlorothiazide pendant de longues périodes peut augmenter le risque de certains cancers de la peau.

  • Informez votre médecin si vous avez déjà été traité pour un cancer de la peau.

  • Informez votre médecin de tout grain de beauté nouveau ou modifié ou de toute marque inquiétante sur votre peau.

  • Utilisez un écran solaire en cas de forte exposition au soleil. Ne pas utiliser de banc solaire.

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Can triamterene cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with triamterene. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common triamterene side-effects (these affect fewer than 1 in 10 people)

Que puis-je faire si je suis confronté à cette situation ?

Se sentir malade (nausées) ou être malade (vomissements)

Stick to simple foods - avoid fatty or spicy meals. Try taking the capsules after a meal or a snack

Diarrhée

Boire beaucoup d'eau pour remplacer les liquides perdus

Modification des résultats de certains tests sanguins

Votre médecin vérifiera ce point de temps en temps

Si vous ressentez d'autres symptômes qui pourraient être dus aux gélules, demandez conseil à votre médecin ou à votre pharmacien.

How to store triamterene

  • Conservez tous les médicaments hors de la portée et de la vue des enfants.

  • Conserver dans un endroit frais et sec, à l'abri de la chaleur et de la lumière directes.

Informations importantes sur tous les médicaments

Informations importantes sur tous les médicaments

Ne dépassez jamais la dose prescrite. Si vous pensez que vous ou quelqu'un d'autre avez pris une dose excessive de ce médicament, rendez-vous au service des accidents et des urgences de votre hôpital local. Emportez la boîte avec vous, même si elle est vide.

Ce médicament est pour vous. Ne le donnez jamais à d'autres personnes, même si leur état semble être le même que le vôtre.

If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking.

Ne gardez pas les médicaments périmés ou dont vous ne voulez plus. Apportez-les à votre pharmacie locale qui les éliminera pour vous.

Si vous avez des questions sur ce médicament, demandez à votre pharmacien.

Signaler les effets secondaires d'un médicament ou d'un vaccin

Si vous ressentez des effets secondaires, vous pouvez les signaler en ligne sur le site web de la carte jaune.

Autres lectures et références

Historique de l'article

Les informations contenues dans cette page sont rédigées et évaluées par des cliniciens qualifiés.

  • Prochaine révision prévue : 5 mai 2028
  • 5 mai 2025 | Dernière version

    Dernière mise à jour par

    Michael Stewart, MRPharmS

    Examiné par des pairs

    Sid Dajani
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